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Cocaine liberation from body packets in an in vitro model

Annals of Emergency MedicinePublished 1 November 1992
Steven E. Aks, Todd L Vander Hoek, Daniel Hryhorczuk, Adam Negrusz, Ian R. Tebbett
Citations30
SJR quartileQ1
SJR score0.84
SNIP1.55

TL;DR

Cocaine liberation of a known quantity of drug is dependent on the wrapping method and material used; thus, a good history from the "body-stuffer" is essential to predict potential cocaine liberation and toxicity.

Abstract

Cocaine liberation of a known quantity of drug is dependent on the wrapping method and material used; thus, a good history from the "body-stuffer" is essential to predict potential cocaine liberation and toxicity. Rapid hydrolysis of cocaine to its inactive metabolite in an alkaline medium implies a role for gastric alkalinization in the acute management of these patients.

Keywords

PsychologyMedicinePharmacology, Toxicology and Pharmaceutics