The art of replication
ThoraxPublished 28 April 2009Open access
Michael Kabesch
Citations5
SJR quartileQ1
SJR score2.45
SNIP2.08
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TL;DR
The asthma candidate genes studied in the replication approach by Blakey and colleagues1 ( pages 381–7 ) were originally discovered by positional cloning, a technique based on linkage studies using microsatellite markers and subsequent fine mapping of these linkage signal loci in families.
Abstract
Extensive loss of the ureter is a potential complication of surgery performed to relieve ureteral obstruction caused by retroperitoneal fibrosis. The authors describe four cases in which renal autotransplantation restored normal urinary drainage. The preoperative evaluation and technicalities of renal autotransplantation are reviewed, The advantages of this procedure, as compared to ileal substitution, for patients with extensive ureteral loss are discussed.
Keywords
Medicine
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