Vitamin A absorption in children with ascariasis
British Journal Of NutritionPublished 1 May 1993Open access
Faruk Ahmed, Md. Mohiduzzaman, Alan A. Jackson
Citations39
SJR quartileQ2
SJR score0.90
SNIP0.91
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TL;DR
The effect of Ascaris lumbricoides infection on retinol absorption was investigated in young children from a slum area of Dhaka City, Bangladesh and the contention that infection with Ascar is predisposes to malabsorption of vitamin A is not supported.
Abstract
The effect of Ascaris lumbricoides infection on retinol absorption was investigated in young children from a slum area of Dhaka City, Bangladesh. Twenty-four children aged 4-10 years were screened and in every case eggs of either Ascaris, Trichuris or hookworm were isolated from the stool. The average serum retinol was 0.91 (SD 0.35) mumol/l and sixteen children had levels below 1.05 mumol/l. This compared with a serum retinol concentration of 1.70 (SD 0.52) mumol/l in five reference children from a more privileged social background. An oral dose of retinol (41.8 mumol) was given to ten children in whom the concentration of Ascaris eggs in the stool varied. Less than 1% of the supplement could be recovered in the stools collected over the following 48 h. Ascaris worms were isolated from the stool and assayed for retinol content. In no case was retinol detected in the worms. These findings do not support the contention that infection with Ascaris predisposes to malabsorption of vitamin A.
Keywords
Immunology and MicrobiologyMedicineNursing
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