The long-term outcomes of depression up to 10 years after stroke; the South London Stroke Register
Journal of Neurology Neurosurgery & PsychiatryPublished 25 October 2013
Luis Ayerbe, Salma Ayis, Siobhan Crichton, Charles Wolfe, Anthony G. Rudd
Citations163
SJR quartileQ1
SJR score3.38
SNIP2.41
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Investigation of the associations between depression and mortality, stroke recurrence, disability, cognitive impairment, anxiety and quality of life (QoL), up to 5 years post-stroke found depression is independently associated with poor health outcomes.
Abstract
Depression is independently associated with poor health outcomes.
Keywords
Medicine
The LancetDisability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
9,004 Citations2012Christopher J L Murray, Theo Vos +360 more
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.
Journal of the American Geriatrics SocietyThe Mini‐Mental State Examination: A Comprehensive Review
5,133 Citations1992Tom N. Tombaugh, Nancy J. McIntyre
The purpose of this paper is to provide a comprehensive review of information accumulated over the past 26 years regarding the psychometric properties and utility of the Mini‐Mental State Examination (MMSE).
PubMedExperience from a multicentre stroke register: a preliminary report.
1,525 Citations1976Kentaro Hatano
In collaboration with 15 centres in 10 countries of Africa, Asia, and Europe, WHO started a pilot study of a community-based stroke register, with standardized methods, with preliminary data obtained on 6395 new cases of stroke in defined study communities from May 1971 to September 1974.
Journal of Affective DisordersEpidemiology of depression and diabetes: A systematic review
1,179 Citations2012Tapash Roy, Cathy E. Lloyd
Current research suggests that the risk of developing depression is increased in people with diabetes; however, further studies are required in order to establish the nature of the relationship between depression, glycaemic control and the development of diabetes complications, and make appropriate recommendations for treatment and to support self-management of diabetes.
The British Journal of PsychiatryNatural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis
968 Citations2013Luis Ayerbe, Salma Ayis +2 more
Major predictors of depression are disability, depression pre-stroke, cognitive impairment, stroke severity and anxiety, and lower quality of life, mortality and disability are independent outcomes of depression after stroke.
International Journal of Geriatric PsychiatryDepression and the risk for cardiovascular diseases: systematic review and meta analysis
963 Citations2007Koen Van der Kooy, Hein van Hout +4 more
Depression and cardiovascular diseases are both common among elderly and depression is suspected to be an independent risk factor for the onset of coronary heart disease, yet it is not clear to what extent and if depression also is associated with the start of other diseases of the circulatory system.
JAMADepression and Risk of Stroke Morbidity and Mortality
815 Citations2011An Pan, Qi Sun +3 more
Depression is associated with a significantly increased risk of stroke morbidity and mortality, consistent across most subgroups.
StrokeMajor depression in stroke patients. A 3-year longitudinal study.
695 Citations1993Maria Åström, Rolf Adolfsson +1 more
Evidence is provided of a differentiation of factors likely to be implicated in the development of depression after stroke based on the period of time since the stroke event.
The LancetDepression after stroke and lesion location: a systematic review
651 Citations2000Alan Carson, Siobhán MacHale +5 more
This systematic review offered no support for the hypothesis that the risk of depression after stroke is affected by the location of the brain lesion.
Europe PMC (PubMed Central)Experience from a multicentre stroke register: a preliminary report
643 Citations1976Hatano, S.
PsychosomaticsValidity of the Beck Depression Inventory, Hospital Anxiety and Depression Scale, SCL-90, and Hamilton Depression Rating Scale as Screening Instruments for Depression in Stroke Patients
577 Citations2002Ivo Aben, Frans R.J. Verhey +3 more
This study evaluated the depression screening abilities of three questionnaires and one observer-rated scale in 202 consecutive patients 1 month after they experienced their first-ever ischemic stroke and concluded that all scales were acceptable screening instruments for poststroke depression.
StrokeReliability of the National Institutes of Health Stroke Scale
483 Citations1997Larry B. Goldstein, Gregory P. Samsa
These data extend the previously demonstrated reliability of the NIHSS to non-neurologists and show that both a variety of physician investigators and nurse study coordinators can be rapidly trained to reliably apply the scale in the context of an actual clinical trial.
American Journal of PsychiatryAssociation of depression with 10-year poststroke mortality
472 Citations1993Philip L.P. Morris, Robert G. Robinson +3 more
It is indicated that depressed mood following stroke is associated with an increased risk of subsequent mortality, and patients who are depressed and socially isolated seem to be particularly vulnerable.
International Journal of StrokeFunctional Outcome Measures in Contemporary Stroke Trials
395 Citations2009Terence J. Quinn, Jesse Dawson +2 more
Heterogeneity in the use of functional outcome measures in stroke trials compromises comparison and meta-analysis, and trialists continue to use poorly validated approaches to outcome assessment.
British Journal of Neuroscience NursingReliability of the National Institutes of Health Stroke Scale
384 Citations2022Alison McLoughlin, Philippa Olive +1 more
It is indicated that reliability of the NIHSS may be lower than anticipated, and further research is needed to better understand the poor reliability, as this has implications for care decisions and patient outcomes.
Journal of Psychosomatic ResearchThe Hospital Anxiety and Depression Scale: A diagnostic meta-analysis of case-finding ability
377 Citations2010Cathy Brennan, Anne Worrall‐Davies +3 more
Clinical RehabilitationShoulder pain after stroke: a review of the evidence base to inform the development of an integrated care pathway
352 Citations2002Lynne Turner‐Stokes, Diana Jackson
Although a complex variety of physical changes are associated with HSP, these broadly divide into ‘flaccid’ and ‘spastic’ presentations, which require co-ordinated multidisciplinary management to minimize interference with rehabilitation and optimize outcome.
StrokeAssessment of scales of disability and handicap for stroke patients.
335 Citations1991Charles Wolfe, N A Taub +2 more
The Barthel scale is a more reliable and less subjective scale for assessing disability, from which a Rankin handicap score can then be derived to enable those managing stroke patients to assess aspects of handicap as well as disability.
The British Journal of PsychiatryMood Disorders in the Year after First Stroke
293 Citations1991Allan House, Martin Dennis +4 more
While there was a high cumulative incidence of psychiatric disorder, little of it persisted: only two cases of major depression were present for the whole 12 months and undue emphasis has been placed on major depression as a specific syndrome following stroke.
The British Journal of PsychiatryDepressed Mood After Stroke
289 Citations1987Derick T Wade, J Legh-Smith +1 more
A community study on stroke registered 976 patients, and path analysis showed that most depression was not explained by factors associated with depression, including loss of functional independence, a low level of other activities, and being female and living with someone.
Psychosomatic MedicineAnxiety, Depression, and Cause-Specific Mortality: The HUNT Study
264 Citations2007Arnstein Mykletun, Ottar Bjerkeset +4 more
Investigation of the association between anxiety/depression and cause-specific mortality with particular attention to the underlying mechanisms and causes of death found depression is a risk factor for all major disease-related causes ofdeath; it is not limited to CVD mortality or suicide.
The Journals of Gerontology Series AThe Association of Depression and Mortality in Elderly Persons: A Case for Multiple, Independent Pathways
257 Citations2001Dan G. Blazer, Celia F. Hybels +1 more
Unlike other known risk factors for mortality in the elderly population, depression appears to be associated with mortality through a number of independent mechanisms, perhaps through complex feedback loops.
Age and AgeingThe Abbreviated Mental Test: Its Use and Validity
254 Citations1991Sutthichai Jitapunkul, Isweri Pillay +1 more
A short version (the AMT7) of the Abbreviated Mental Test was developed, whose validity, internal consistency and coverage of domains was equivalent to the AMT but it had a slightly higher sensitivity (with acceptable specificity) than the original.
Cochrane Database of Systematic ReviewsSelective serotonin reuptake inhibitors (SSRIs) for stroke recovery
245 Citations2012Gillian Mead, Cheng‐Fang Hsieh +5 more
WhetherSSRIs improve recovery after stroke, and whether treatment with SSRIs was associated with adverse effects, was determined, and there were statistically significant benefits of SSRI on both of the primary outcomes.
StrokeThe Natural History of Depression up to 15 Years After Stroke
201 Citations2013Luis Ayerbe, Salma Ayis +3 more
The natural history of depression after stroke is dynamic, and depression affects most of the stroke patients with episodes that have a short duration but a high risk of recurrence in the long term.
StrokeNatural History, Predictors, and Associations of Depression 5 Years After Stroke
178 Citations2011Luis Ayerbe, Salma Ayis +3 more
Frequency of depression up to 5 years after stroke is 30%; however, it is a dynamic situation with recovery and new cases diagnosed over time, which supports the need for regular assessment of depression and its associated factors and for the development of effective interventions to reduce depression after stroke.
Archives of Physical Medicine and RehabilitationQuality of Life of Stroke Survivors: A 1-Year Follow-Up Study
171 Citations2006Timothy Kwok, Raymond Lo +4 more
Depression has a more generalized adverse effect on HRQOL than basic functional disabilities and health care professionals should focus on treating depression; group exercises and self-help group activities may help in promoting socialization and reintegration into community life.
Clinical RehabilitationDepression after stroke: a review of the evidence base to inform the development of an integrated care pathway. Part 1: Diagnosis, frequency and impact
158 Citations2002Lynne Turner‐Stokes, Nibras Hassan
A systematic review of published studies on depression in stroke found that the Beck Depression Inventory, Hamilton Depression Rating Scale and Zung Self-rating Depression Scale were most commonly used and have demonstrable validity in stroke patients but tend to exclude those with aphasia.
StrokeEthnic Group Disparities in 10-Year Trends in Stroke Incidence and Vascular Risk Factors
147 Citations2008Peter U. Heuschmann, Andy P. Grieve +3 more
The greatest decline in incidence was observed in black women, but ethnic group disparities still exist, indicating a higher stroke risk in black people compared to white people.
StrokeIsolated Nodular Infarction
139 Citations2008In Soo Moon, Ji Soo Kim +6 more
The findings of isolated nodular infarctions are consistent with impaired gravito-inertial processing of the vestibular signals and disrupted nodular inhibition on the Vestibular secondary neurons and the velocity storage mechanism.
Australian & New Zealand Journal of PsychiatryDepression, Introversion and Mortality following Stroke
111 Citations1993Philip L.P. Morris, Robert G. Robinson +1 more
It is concluded that personality introversion and depression are associated with increased mortality following stroke.
StrokePsychosocial Problems, Quality of Life, and Functional Independence Among Indian Stroke Survivors
103 Citations2010Rinu Susan Raju, P.S. Sarma +1 more
The presence of anxiety, depression, and functional dependence were associated with impaired QoL and older age and stroke severity resulted in increased functional dependence.
General Hospital PsychiatryEarly detection of patients at risk for anxiety, depression and apathy after stroke
83 Citations2009Ulrike Sagen, Arnstein Finset +5 more
Assessment with HADS within the first 2 weeks of stroke can contribute to the detection of patients at risk for clinically significant anxiety, depression and apathy at 4 months after stroke.
Journal of Affective DisordersDepressive symptoms in stroke patients: A 13 month follow-up study of patients referred to a rehabilitation unit
79 Citations2010Lasse Farner, Jørgen Wagle +4 more
Changes in depressive symptoms in elderly stroke patients across a timespan of one year are described to examine risk factor for such changes and to explore whether depressive symptoms have any independent impact upon one year mortality and nursing home placement.
Sao Paulo Medical JournalSelective serotonin reuptake inhibitors (SSRIs) for stroke recovery
79 Citations2013Gillian Mead, Cheng‐Fang Hsieh +5 more
If SSRIs are more effective than placebo or usual care at improving outcomes in people less than 12 months post-stroke, and to determine whether treatment withSSRIs is associated with adverse effects.
BMJSurvival differences after stroke in a multiethnic population: follow-up study with the south London stroke register
70 Citations2005Charles Wolfe, Nigel Smeeton +3 more
In general, black patients in a south London population with first ever stroke are more likely to survive than white patients, the exceptions being in those aged < 65 and those with a prior Barthel score < 15.
Journal of Neurology Neurosurgery & PsychiatryPredicting independent survival after stroke: a European study for the development and validation of standardised stroke scales and prediction models of outcome
33 Citations2012Salma Ayis, Bola Coker +3 more
Living alone before the stroke was not significantly associated with independent survival after the stroke, and five variables provided good prediction for all populations and subgroups.