A case‐control study of the efficacy of a non‐randomized breast cancer screening program in florence (Italy)

International Journal of CancerPublished 15 October 1986

Domenico Palli, Marco Rosselli Del Turco, Eva Buiatti, Simona Carli, Stefano Ciatto, Lucia Toscani

DOI10.1002/ijc.2910380408

Source URL

Citations196

SJR quartileQ1

SJR score2.25

SNIP1.76

TL;DR

In a rural area near Florence a population‐based screening program for breast cancer was started in 1970, offering a mammography test every 2.5 years to all women between 40 and 70 years of age, a case‐control study has been carried out comparing the screening history of all women who died from breast cancer in this area in the years 1977–1984 with that of a matched group of living controls.

Abstract

In a rural area near Florence a population-based screening program for breast cancer was started in 1970, offering a mammography test every 2.5 years to all women between 40 and 70 years of age. In order to evaluate the efficacy of this program a case-control study has been carried out comparing the screening history of all women who died from breast cancer in this area in the years 1977-1984, and who had been diagnosed after the start of the program, with that of a matched group of living controls. The case-control study showed that the overall O.R. of dying from breast cancer in the study period for "screened" versus "never-screened" women was 0.53 (95% C.I. = 0.29-0.95). After evaluation of other variables as potential confounders the adjusted O.R. estimates were respectively 0.57 (95% C.I. = 0.35-0.92) and 0.32 (95% C.I. = 0.20-0.52) for women screened only once or at least twice. No significant protective effect was shown for women below the age of 50 years.

Keywords

Medicine

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