Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors
Journal of Clinical EpidemiologyPublished 1 July 2004
Christopher H. Schmid, Paul C. Stark, Jesse A. Berlin, Paul Landais, Joseph Lau
Citations236
SJR quartileQ1
SJR score3.15
SNIP2.66
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TL;DR
The first investigation found meta-regression most effective for detecting treatment interactions with study-level factors in meta-analyses with >10 studies, heterogeneous treatment effects, or significant overall treatment effects when treatment effects are heterogeneous.
Abstract
Meta-regression can detect interactions of treatment with study-level factors when treatment effects are heterogeneous. Individual patient data are needed for patient-level factors and homogeneous effects.
Keywords
MathematicsDecision Sciences
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