Age-Related Cognitive Deficits Mediated by Changes in the Striatal Dopamine System
American Journal of PsychiatryPublished 1 April 2000
Lars Bäckman, Nathalie Ginovart, Roger A. Dixon, Tarja‐Brita Robins Wahlin, Åke Wåhlin, Christer Halldin
Citations465
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
D(2) receptor binding is a more important factor than chronological age in accounting for variation in cognitive performance across the adult lifespan, and changes in dopamine neurotransmission play an important role in aging-related cognitive decline.
Abstract
D(2) receptor binding is a more important factor than chronological age in accounting for variation in cognitive performance across the adult lifespan. Changes in dopaminergic neurotransmission play an important role in aging-related cognitive decline.
Keywords
MedicineNeuroscience
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