Co-release of neuropeptide Y and catecholamines during physical exercise in man
Biochemical and Biophysical Research CommunicationsPublished 1 November 1985
Jan M. Lundberg, Arne Martinsson, Anette Hemsén, Elvar Theodorsson, Jan Svedenhag, Björn Ekblom
Citations223
SJR quartileQ2
SJR score0.75
SNIP0.56
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TL;DR
Venous plasma levels of neuropeptide Y-like immunoreactivity increased in parallel with catecholamines, heart rate and blood pressure during graded physical exercise in man, suggesting release of a neural origin.
Abstract
Venous plasma levels of neuropeptide Y-like immunoreactivity (with chromatographic properties of synthetic neuropeptide Y) increased in parallel with catecholamines, heart rate and blood pressure during graded physical exercise in man. The plasma levels of neuropeptide Y correlated better with the levels of noradrenaline than adrenaline, suggesting release of a neural origin. Taken together with previous results, this suggests that neuropeptide Y is released together with noradrenaline upon sympathetic activation during physiological conditions in man. Determinations of plasma neuropeptide Y may therefore be valuable in the assessment of sympathetic nerve activity.
Keywords
Agricultural and Biological SciencesNeuroscienceBiochemistry, Genetics and Molecular Biology
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