Pictorial review: Imaging of peripheral nerve tumours
Clinical RadiologyPublished 1 January 1997
Ian Beggs
Citations83
SJR quartileQ2
SJR score0.62
SNIP0.85
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TL;DR
Characteristic locations and appearances help to define nerve tumours although the imaging findings of nerve and other soft tissue tumours overlap.
Abstract
The ultrasound, computed tomography and magnetic resonance features of extracranial nerve tumours are reviewed. Characteristic locations and appearances help to define nerve tumours although the imaging findings of nerve and other soft tissue tumours overlap.
Keywords
Medicine
Plastic & Reconstructive SurgerySoft Tissue Tumors
2,287 Citations1985Franz M. Enzinger, Sharon W. Weiss +1 more
RadiologyPeripheral nerves of the extremities: imaging with US.
359 Citations1988Bruno D. Fornage
High-resolution real-time ultrasonography was effective in imaging nerve masses in the extremities, and large normal nerves can now be demonstrated with high-resolution US.
RadiologyPeripheral (extracranial) nerve tumors: correlation of MR imaging and histologic findings.
277 Citations1992Jin‐Suck Suh, Pascual Abenoza +3 more
Magnetic resonance images of 16 peripheral nerve tumors (14 patients) were correlated with histopathologic appearance and appeared to correspond to a distinctive zonal histologic appearance that was found only in the neurofibromas.
Skeletal RadiologyMagnetic resonance appearance of peripheral nerve sheath tumors
210 Citations1991M A Stull, Richard P. Moser +3 more
MRI accurately determined the relationship between the lesion and the adjacent neurovascular structures and muscles, thereby assisting surgical management and suggesting a peripheral nerve sheath neoplasm.
Journal of Computer Assisted TomographyMR of Benign Peripheral Nerve Sheath Tumors
182 Citations1991E Cerofolini, Antonio Landi +4 more
In patients with soft tissue masses, MR may contribute to recognition of nerve sheath tumors by showing the nerve of origin and typical signal hyperintensity on T2-weighted images and it can also be helpful in distinguishing between schwannomas and neurofibromas by the location of the nerve in origin and the presence of a capsule.
American Journal of RoentgenologyBenign schwannomas: pathologic basis for CT inhomogeneities
178 Citations1986Cohen Lm, AM Schwartz +1 more
It is concluded that schwannomas may have areas of mixed attenuation on CT, that these areas can probably be explained by distinct findings on pathologic examination, and that inhomogeneity can represent benign or malignant disease.
RadiologyMorton neuroma: sonographic evaluation.
177 Citations1989RICHARD A. REDD, V J Peters +3 more
One hundred consecutive patients with symptoms suggestive of Morton neuroma were examined with sonography, and 134 intermetatarsal masses were demonstrated; forty-five patients underwent surgical exploration, which revealed Morton neuromas.
Journal of Computer Assisted TomographyMR Imaging of Extracranial Nerve Sheath Tumors
167 Citations1992Datla G. K. Varma, Lia A. Moulopoulos +5 more
Magnetic resonance imaging cannot distinguish schwannomas from neurofibromas, and benign tumors may mimic malignant NSTs when cystic, hemorrhagic, and necrotic degeneration is present, so evaluation of this sign with assessment of location and growth along nerves may help to avoid confusion with other lesions.
American Journal of RoentgenologyMalignant nerve-sheath neoplasms in neurofibromatosis: distinction from benign tumors by using imaging techniques
151 Citations1987Errol Levine, Manop Huntrakoon +1 more
67Ga scintigraphy appears promising as a screening technique to identify lesions with malignant degeneration in patients with neurofibromatosis, and CT and MR could not generally distinguish malignant from benign lesions with certainty.
Journal of Computer Assisted TomographyComputed Tomography of Extracranial Nerve Sheath Tumors with Pathological Correlation
132 Citations1983Ashok J. Kumar, Francis P. Kuhajda +4 more
Histological examination of hypodense lesions revealed five factors contributing to reduced attenuation values, including a population of lipid-rich Schwann cells and the presence of adipocytes (transformed fibroblasts) in neurofibromas.
RadiologySpinal and paraspinal neurofibromatosis: surface coil MR imaging at 1.5 T1.
120 Citations1987Dan L. Burk, James A. Brunberg +3 more
The ability to obtain high-resolution, multiplanar images in a noninvasive fashion makes surface coil MR imaging an ideal technique for evaluating neurofibromatosis involving the spinal cord, spinal canal, and paraspinal soft tissues.
American Journal of RoentgenologyIntrathoracic neurogenic tumors: MR-pathologic correlation.
114 Citations1992Fumikazu Sakai, S Sone +8 more
An MR-pathologic correlation of nine intrathoracic neurogenic tumors (three neurofibromas, four schwannomas, and two ganglioneuromas) was performed to characterize their MR appearances.
American Journal of RoentgenologyRetroperitoneal neurilemoma: CT and MR findings.
107 Citations1992S H Kim, B I Choi +2 more
CT findings of a round mass with prominent cystic degeneration, along with certain MR imaging characteristics, may be helpful in the preoperative diagnosis of retroperitoneal neurilemomas.
American Journal of RoentgenologyIntradural schwannomas of the spine: MR findings with emphasis on contrast-enhancement characteristics.
102 Citations1992David P. Friedman, L M Tartaglino +1 more
Recognition of the MR characteristics of intradural extramedullary schwannomas may be helpful in the differential diagnosis of spinal tumors, in particular, peripheral contrast enhancement of an intradial extramingullary tumor on MR images should suggest the diagnosis ofschwannoma.
Malignant Tumors of Peripheral Nerves
102 Citations2014Simon C. Kao, David M. Parham +1 more
From the microscopic standpoint, the majority of MPNSTs are hypercellular, high grade spindle cell sarcomas with plentiful mitoses, often with some degree of nuclear pleomorphism and/or necrosis, and variable positivity for S100, SOX10, EMA, CD34, Nestin, GFAP, collagen IV, and p53 by immunohistochemistry.
RadiologyInterdigital (Morton) neuroma: high-resolution MR imaging with a solenoid coil.
93 Citations1991S J Erickson, P B Canale +6 more
Fifteen patients with symptoms suggestive of plantar interdigital neuroma underwent magnetic resonance (MR) imaging at 1.5 T with a solenoid forefoot coil with an 8-cm field of view, and five of these, in feet that underwent surgery, were pathologically confirmed neuromas.
RadiologyBenign extraaxial tumors: contrast enhancement with Gd-DTPA.
93 Citations1987R K Breger, R A Papke +4 more
RadiologyMorton neuroma: evaluation with MR imaging performed with contrast enhancement and fat suppression.
92 Citations1993Michael R. Terk, Phillip K. Kwong +3 more
In patients who need imaging confirmation of a clinically suspected Morton neuroma, the combination of fat suppression and contrast enhancement provides reliable high-contrast images.
American Journal of RoentgenologyCT of sarcomatous degeneration in neurofibromatosis
88 Citations1983BG Coleman, Arger Ph +4 more
In six of seven subsequently proven neurofibrosarcomas, CT demonstrated low-density areas that histopathologically appeared to be due to necrosis, hemorrhage, and/or cystic degeneration.
American Journal of RoentgenologyImaging findings in a patient with fibrolipomatous hamartoma of the median nerve.
84 Citations1993Massimo Cavallaro, John A.M. Taylor +3 more
British Journal of RadiologyUltrasound appearances of peripheral nerve tumours
69 Citations1986David G. Hughes, David J. Wilson
A 68-year-old woman had a history of a lump in the right popliteal fossa for 3 years that had been slowly increasing in size and had recently become painful and produced pain radiating down to the instep.
Journal of neurosurgeryUltrasound diagnosis of an intraneural ganglion cyst of the peroneal nerve
62 Citations1992Frans S. S. Leijten, Willem-Frans Arts +1 more
The authors present the case of an intraneural ganglion cyst of the peroneal nerve, diagnosed by means of ultrasound, which also gave an exact definition of its size and location, confirmed at operation.
Journal of Computer Assisted TomographyMR Imaging of Spinal Neurinomas with Pathological Correlation
60 Citations1990Hiroshi Demachi, Tsutomu Takashima +6 more
Eight patients with nine spinal neurinomas were examined with magnetic resonance (MR) imaging, and it was impossible to establish a correlation between Antoni A and Antoni B tissue types and features recognized on T1WIs and T2WIs.
Skeletal RadiologyMRI of postamputation neuromas
57 Citations1990RolandoD. Singson, Frieda Feldman +4 more
Magnetic resonance imaging of 24 symptomatic lower limb amputations revealed that postamputation neuromas were easily diagnosed in above-the-knee amputees and showed additional causes of stump pain such as scar formation, fat in atrophied muscles, soft tissue abscesses, osteomyelitis, and hematomas.
PubMedSonographic analysis of Morton's neuroma.
54 Citations1993Richard Pollak, R A Bellacosa +3 more
Evidence is provided that preoperative sonography is an additional aid in the evaluation of Morton's neuroma, and previous evidence that symptomatic neuromas are likely to be at least 5 mm.
RadiologyPostamputation neuromas and other symptomatic stump abnormalities: detection with CT.
52 Citations1987R D Singson, Frieda Feldman +4 more
Computed tomography was performed on ten lower limb amputees with stump pain; five patients had neuromas that were manifest as focal or generalized alteration in the caliber, size, or contour of the nerve trunk in the affected stump.
NeuroradiologyExtracranial and extraspinal nerve sheath tumors: Computed tomographic evaluation
44 Citations1988M Chui, Bruce Bird +1 more
None of the schwannomas appeared homogeneously hypodense on IV enhanced CT, whereas close to half of neurofibromas and plexiform neurofipromas were so, and this fact may be related to differences in inherent vascularity and blood-nerve barrier (fenestrated blood vessels), which may be a useful distinguishing CT feature.
American Journal of RoentgenologyPlexiform neurofibromatosis of the mediastinum: CT appearance
44 Citations1988PM Bourgouin, J A Shepard +2 more
Patients with pathologically proved thoracic plexiform neurofibromatosis showed an infiltrative process and masses that involved the mediastinum along the distribution of the sympathetic chains, phrenic, and vagus nerves, and CT revealed calcifications and peripheral enhancement of nodular components after IV infusion of contrast material.
Journal of Computer Assisted TomographyMalignant Schwannomas of the Thorax
36 Citations1993Woo Kyung Moon, Jung-Gi Im +1 more
CT of eight patients with malignant schwannomas arising in the thorax found the presence of low-density areas, compression of adjacent structures, pleural abnormalities, such as pleural effusion or pleural nodules, and metastatic pulmonary nodules.
Acta RadiologicaMr Imaging of Benign Peripheral Nerve Sheath Tumors
36 Citations1994Veli Söderlund, H. Göranson +1 more
NeuroradiologySignal intensity correlation of MRI with pathological findings in spinal neurinomas
35 Citations1992Haitao Hu, Qingshui Huang
The similarity of the T1 values of neurinomas to that of the spinal cord may be related to the abundance of Schwann cells within the tumors, but tumors hypointense to cord and tumors isointense to Cord on T1WI showed no significant difference in their gross and microscopic pathology.
Journal of Neurology Neurosurgery & PsychiatryIntraneural ganglion of the sciatic nerve: detection by ultrasound.
34 Citations1994C. Lang, U. Neubauer +2 more
It is of note that despite antiviral treatment, this patient died within six weeks, and an immunologically mediated injury triggered by the herpes infection could also be involved here, as in another patient with HSV-1 myelitis whose necropsy examination showed patchy demyelination of the spinal cord.
Clinical RadiologyDirect and indirect MRI findings in ganglion cysts of the common peroneal nerve
33 Citations1995Fergus V. Coakley, David B. Finlay +2 more
MRI findings in three cases of ganglion cyst of the common peroneal nerve are presented, finding increased signal on both T1- and T2-weighted images was noted throughout the per oneal compartment and was associated with clinical and EMG evidence of denervation.
PubMedSonography of peripheral nerves of the extremities.
29 Citations1993Bruno D. Fornage
The examination of nerves in the extremities is a promising new application of high resolution US and can play a significant role in the diagnosis of pathologic conditions of nerves, particularly nerve sheath tumors, at a lower cost than MRI.
PubMedComputed tomography for diagnosis of Morton's neuroma.
28 Citations1991İbrahim Turan, Urban Lindgren +1 more
Fifteen patients suspected to have Morton's neuroma were examined by computed tomography, which revealed the neuroma in seven cases, and all seven underwent surgery and had the diagnosis confirmed.
European Journal of RadiologyMyxoid intraneural cysts of external popliteal ischiadic nerve. Report of 2 cases studied with ultrasound, computed tomography and magnetic resonance imaging
27 Citations1992Carlo Masciocchi, M Innacoli +4 more
Two cases of peripheral neuropathy of the external popliteal ischiadic nerve caused by intraneural cysts evaluated with ultrasound, computed tomography and magnetic resonance and provide information about the involvement of the neighboring areas, which are useful indications for possible surgical treatment of the disease.
Skeletal RadiologyCase report 814
26 Citations1993H Declercq, R. De Man +3 more
The purpose of this report was to point out a characteristic sign of fibrolipoma, which in the author's opinion allows distinction on CT and MRI between fibrolIPoma and the other peripheral nerve and fatty soft tissue tumors.
Skeletal RadiologyVascularization of peripheral neurilemomas: angiographic, computed tomographic, and histologic studies
26 Citations1986Ö. Berlin, Bertil Stener +3 more
The vascularization of peripheral neurilemoma was studied in 17 patients, in eight by angiography and in 16 by computed tomography (CT) using contrast enhancement, and showed that Antoni-A tissue was rich in small and medium-sized vessels, whereas large vessels were more frequently seen in AntonI-B tissue.
Clinical RadiologyCase report: Imaging of widespread plexiform neurofibromatosis
23 Citations1993K. Gossios, R. Guy
The case of a woman with peripheral neurofibromatosis who presented with loin pain is presented and plexiform neuro fibromas were present in the mediastinum, liver, mesentery and psoas muscles.
Journal of Computer Assisted TomographyMR Imaging of Stump Neuroma
21 Citations1990John F. Donnal, Russell A. Blinder +3 more
A case is reported in which magnetic resonance allowed precise preoperative diagnosis and localization of a lesion in the postamputation patient, and magnetic resonance, with its ability for long axis imaging in the extremity, is ideally suited for the workup of stump neuromas.
Journal of Computer Assisted TomographySpinal Neurilemmomas and Neurofibromas
19 Citations1993A. Gouliamos, Dimitrios S. Kontogiannis +4 more
The MR studies of three histologically proven spinal neurilemmomas and neurofibromas were reviewed retrospectively and the common characteristic of these cases was a central low intensity focus seen on postcontrast T1-weighted imaging.
Skeletal RadiologyOpenquiz-solution: Case report 676
19 Citations1991IreneO. Gleason-Jordan, JosephM. Mirra +2 more
A rare case of metastatic, lethal, malignant granular cell tumor is presented in a 77-year-old woman, which involved numerous sites, including the skeleton, and the differential diagnosis was considered in detail.
Acta RadiologicaCT Morphology of Benign Median Nerve Tumors
18 Citations1990Thomas Feyerabend, Rainer Schmitt +2 more
Computed tomography was performed in 3 patients with benign tumors of the median nerve, histologically confirmed as neurilemmoma, fibrolipoma and hemangioma, which gave useful information regarding the anatomic location, size, and relationship of peripheral nerve sheath tumors to surrounding structures.
Acta RadiologicaMR Imaging of Spinal Neurofibromatosis
18 Citations1991M. H. Li, S. Holtås
The study shows that MR imaging is the modality of choice for evaluating most aspects of spinal and paraspinal neurofibromatosis.
NeurologyUlnar neuropathy due to a carpal ganglion
16 Citations1990G Giuliani, M Poppi +2 more
Clinical features and electrophysiologic studies indicated a lesion of the ulnar nerve in the wrist of a 50-year-old man and CT of this region revealed a ganglion inside Guyon's canal.
Journal of Clinical UltrasoundSonographic features of retroperitoneal neurilemoma
13 Citations1993Chung‐Huang Kuo, Chi‐Sin Changchien
Seven cases of retroperitoneal neurilemoma confirmed by histology had an ultrasound examination, and the sonograms of all 7 cases were consistent with the macroscopic features of the tumors.
Journal of Computer Assisted TomographyComputed Tomography of Elephantiasis Neuromatosa
7 Citations1989Yancu Hertzanu, Menachem Hirsch +2 more
Computed tomography demonstrated the extent of the disease, which is essential if surgery is planned, and an unusually symmetric and grotesque elephantiasis neuromatosa of the trunk is presented.
PubMedRadiologic findings in peripheral neurilemoma.
5 Citations1987Reinbold Wd, B Wimmer +2 more
Radiographic findings using computed tomography, ultrasonography and arteriography are presented and pathologic correlation of peripheral neurilemoma is discussed by using a special immunoperoxidase technique.