Selective Fluorination in Organic and Bioorganic Chemistry
ACS symposium seriesPublished 22 February 1991
Citations418
SJR quartileQ4
SJR score0.18
SNIP0.22
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Abstract
The influence of fluorine on the physical, chemical and biological properties of molecules is described. A discussion of the effect of fluorination on bond lengths and bond strengths is presented in the course of an analysis of the steric demand of fluorinated substituents. These steric effects as well as electronic interactions are illustrated in a discussion of fluorinated vitamin D3 and prostaglandin and thromboxane analogs.
Keywords
ChemistryPharmacology, Toxicology and Pharmaceutics