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Risk Factors for Severe Hepatic Injury After Introduction of Highly Active Antiretroviral Therapy

JAIDS Journal of Acquired Immune Deficiency SyndromesPublished 1 August 2001
Marina Núñez, Raquel Martins Lana, Juan L. Mendoza, Luz Martı́n-Carbonero, Vincent Soriano
Citations246
SJR quartileQ1
SJR score1.04
SNIP0.81

TL;DR

Avoidance of alcohol abuse, especially in study subjects coinfected with HCV, will reduce the risk of hepatic injury after HAART, and older age should be considered.

Abstract

Nearly 10% of study subjects who start HAART experience severe transaminase elevation, irrespective of the treatment. Avoidance of alcohol abuse, especially in study subjects coinfected with HCV, will reduce the risk of hepatic injury after HAART. When possible, prior treatment for chronic HCV infection should be considered.

Keywords

Medicine