Isolation and Characterization of New Anti-HIV and Cytotoxic Leads from Plants, Marine, and Microbial Organisms
Journal of Natural ProductsPublished 1 May 1997
Tawnya C. McKee, Heidi R. Bokesch, Jinping L. McCormick, Mohammad A. Rashid, Dirk Spielvogel, Kirk R. Gustafson
Citations178
SJR quartileQ1
SJR score0.63
SNIP1.12
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TL;DR
New cytotoxic isomalabaricane triterpenes have been isolated from a sponge Stelletta sp.
Abstract
New cytotoxic isomalabaricane triterpenes have been isolated from a sponge Stelletta sp. (1-7); anti-HIV pterocarpans (8 and 9) and isoflavanoids (12-16 and 18) were elucidated from two tropical plants in the genus Erythrina; and anti-HIV enniatins (20 and 22-23) were characterized from fungi in the genera Fusarium and Alternaria. The enniatins were evaluated for in vivo anti-HIV activity in the hollow fiber assay.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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