Blood pressure, heart rate, and plasma catecholamines under resting conditions in rat strains selectively bred for differences in response to stress
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TL;DR
The finding that the strains differ in basal autonomic function as well as in autonomic reactivity suggests that both “basal” and “reactive” dimensions must be considered in attempting a satisfactory explanation of differences in physiological and behavioral response in the Maudsley strains.
Abstract
Maudsley Reactive and Maudsley Nonreactive rats exhibited clear differences in basal physiological function. Under resting conditions, Maudsley Reactive rats had higher systolic and diastolic blood pressure and heart rate and exhibited lower basal plasma NE levels than Nonreactive rats. These results and previous observations suggest that genetic selection for differences in behavioral reactivity has produced fundamental alterations of autonomic function with clear involvement of the sympathetic system. The finding that the strains differ in basal autonomic function as well as in autonomic reactivity suggests that both "basal" and "reactive" dimensions must be considered in attempting a satisfactory explanation of differences in physiological and behavioral response in the Maudsley strains.