Low-Fat Dietary Pattern and Risk of Cardiovascular Disease
JAMAPublished 7 February 2006
Barbara V. Howard, Linda Van Horn, Judith Hsia, JoAnn E. Manson, Marcia L. Stefanick, Sylvia Wassertheil‐Smoller
Citations1,083
SJR quartileQ1
SJR score5.35
SNIP10.71
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
ClinicalTrials.gov Identifier: NCT00000611.
Keywords
Medicine
DiabetologiaHomeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
31,449 Citations1985David R. Matthews, J P Hosker +4 more
The correlation of the model's estimates with patient data accords with the hypothesis that basal glucose and insulin interactions are largely determined by a simple feed back loop.
JAMASummary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
27,886 Citations1993Scott M. Grundy
Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
JAMARisks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial
15,680 Citations2002Jacques E. Rossouw
Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
The LancetEfficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins
6,775 Citations2005Colin Baigent, Anthony Keech +9 more
Statin therapy can safely reduce the 5-year incidence of major coronary events, coronary revascularisation, and stroke by about one fifth per mmol/L reduction in LDL cholesterol, largely irrespective of the initial lipid profile or other presenting characteristics.
CirculationFish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
3,697 Citations2002Penny M. Kris‐Etherton, William S. Harris +1 more
Evidence from epidemiological studies and RCTs will be reviewed, and recommendations reflecting the current state of knowledge will be made with regard to both fish consumption and omega-3 fatty acid (plant- and marine-derived) supplementation.
CirculationMediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction
2,909 Citations1999Michel de Lorgeril, Patricia Salen +4 more
The protective effect of the Mediterranean dietary pattern was maintained up to 4 years after the first infarction, confirming previous intermediate analyses and indicating that a comprehensive strategy to decrease cardiovascular morbidity and mortality should include primarily a cardioprotective diet.
Controlled Clinical TrialsDesign of the Women’s Health Initiative Clinical Trial and Observational Study
2,565 Citations1998
The rationale for the interventions being studied in each of the CT components and for the inclusion of the OS component is described, including a brief description of the scientific and logistic complexity of the WHI.
The LancetMediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
2,134 Citations1994M. de Lorgeril, S. Renaud +7 more
An alpha-linolenic acid-rich Mediterranean diet seems to be more efficient than presently used diets in the secondary prevention of coronary events and death.
New England Journal of MedicineEstrogen plus Progestin and the Risk of Coronary Heart Disease
2,048 Citations2003JoAnn E. Manson, Judith Hsia +13 more
Estrogen plus progestin does not confer cardiac protection and may increase the risk of CHD among generally healthy postmenopausal women, especially during the first year after the initiation of hormone use.
JAMAIntensive Lifestyle Changes for Reversal of Coronary Heart Disease
1,710 Citations1998Dean Ornish
More regression of coronary atherosclerosis occurred after 5 years than after 1 year in the experimental group, and in the control group, coronary Atherosclerosis continued to progress and more than twice as many cardiac events occurred.
Arteriosclerosis and Thrombosis A Journal of Vascular BiologyEffect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials.
1,487 Citations1992Ronald P. Mensink, Mira Katan
All fatty acids elevated HDL cholesterol when substituted for carbohydrates, but the effect diminished with increasing unsaturation of the fatty acids, and that for monounsaturates was not.
Diabetes CareEvidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications
1,174 Citations2002Marion J. Franz, John P. Bantle +10 more
This 2002 technical review provides principles and recommendations classified according to the level of evidence available, and grades nutrition principles into four categories based on the available evidence: those with strong supporting evidence, those with some supporting evidence), those with limited supporting evidence and those based on expert consensus.
American Journal of EpidemiologyUsing Intake Biomarkers to Evaluate the Extent of Dietary Misreporting in a Large Sample of Adults: The OPEN Study
1,055 Citations2003Amy F. Subar
There was little underreporting of the percentage of energy from protein for men or women, and unbiased biomarkers of energy and protein intakes: doubly labeled water and urinary nitrogen have important implications for nutritional epidemiology and dietary surveillance.
Annals of EpidemiologyMeasurement Characteristics of the Women’s Health Initiative Food Frequency Questionnaire
1,016 Citations1999Ruth E. Patterson, Alan R. Kristal +4 more
Comparison of WHI FFQ nutrient intake measures to independent and unbiased measures, such as doubly labeled water estimates of energy expenditure, are needed to help address the validity of the FFQ in this population.
American Journal of Clinical NutritionFruit and vegetable intake and risk of cardiovascular disease: the Women’s Health Study
925 Citations2000Simin Liu, JoAnn E. Manson +5 more
It is suggested that higher intake of fruit and vegetables may be protective against CVD and support current dietary guidelines to increase fruit and vegetable intake.
The LancetEffects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS)
845 Citations1992Gerald F. Watts, B. Lewis +6 more
The findings support the use of a lipid-lowering diet, and if necessary of appropriate drug treatment, in men with CHD who have even mildly raised serum cholesterol concentrations.
JAMALow-Fat Dietary Pattern and Risk of Invasive Breast Cancer
820 Citations2006Ross L. Prentice, Bette J. Caan +46 more
American Journal of Clinical NutritionWhole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study
778 Citations1999Simin Liu, Meir J. Stampfer +6 more
Increased intake of whole grains may protect against CHD, and the lower risk associated with higher whole-grain intake was not fully explained by its contribution to intakes of dietary fiber, folate, vitamin B-6, and vitamin E.
JAMACholesterol Lowering With Statin Drugs, Risk of Stroke, and Total Mortality
738 Citations1997Patricia R. Hebert
Annals of EpidemiologyOutcomes ascertainment and adjudication methods in the women's health initiative
687 Citations2003J. David Curb, Anne McTiernan +9 more
The Women'sHealth Initiative has both observational study and clinical trial components designed to examines simultaneously the impact of a number of factors on many of the major causes of morbidity and mortality in postmeno-pausal women.
Survey of AnesthesiologyCholesterol Lowering With Statin Drugs, Risk of Stroke, and Total Mortality
508 Citations1998Patricia R. Hebert, J. Michael Gaziano +2 more
This overview of all published randomized trials of statin drugs demonstrates large reductions in cholesterol and clear evidence of benefit on stroke and total mortality, but there was no significant evidence for any increases in either non-CVD deaths or cancer incidence.
American Journal of EpidemiologyDietary Fat Intake and Risk of Coronary Heart Disease in Women: 20 Years of Follow-up of the Nurses' Health Study
497 Citations2005Kyungwon Oh
Findings continue to support an inverse relation between polyunsaturated fat intake and CHD risk, particularly among younger or overweight women, and trans-fat intake was associated with increased risk of CHD, particularly for younger women.
CirculationThe Oslo Diet-Heart Study
462 Citations1970Paul Leren
The study deals with 412 men, aged 30 to 64 years, randomized 1 to 2 years after a first myocardial infarction, and found major coronary heart disease relapses, including fatal and nonfatal events (MI), were significantly reduced.
JAMALow-Fat Dietary Pattern and Weight Change Over 7 Years
422 Citations2006Barbara V. Howard, JoAnn E. Manson +10 more
JAMALow-Fat Dietary Pattern and Risk of Colorectal Cancer
393 Citations2006Shirley A.A. Beresford, Karen Johnson +45 more
Among postmenopausal women, a low-fat dietary pattern did not result in a statistically significant reduction in invasive breast cancer risk over an 8.1-year average follow-up period, and the nonsignificant trends observed indicate that longer, planned, nonintervention follow- up may yield a more definitive comparison.
International Journal of EpidemiologyDietary Prevention of Coronary Heart Disease: The Finnish Mental Hospital Study
392 Citations1979Osmo Turpeinen, J MARTTI +4 more
It is concluded that the use of the serum-cholesterol-lowering diet exerted a substantial preventive effect on CHD.
StrokeProspective Study of Major Dietary Patterns and Stroke Risk in Women
232 Citations2004Teresa T. Fung, Meir J. Stampfer +4 more
A dietary pattern typified by higher intakes of red and processed meats, refined grains, and sweets and desserts may increase stroke risk, whereas a diet higher in fruits and vegetables, fish, and whole grains may protect against stroke.
Annals of EpidemiologyThe women's health initiative postmenopausal hormone trials: overview and baseline characteristics of participants
231 Citations2003Marcia L. Stefanick, Barbara B. Cochrane +4 more
The postmenopausal hormone therapy (PHT) component of the Women’s Health Initiative (WHI) is composed of two randomized, placebo-controlled, double-blind trials in post menopausal women aged 50 to 79 years at initial screening, testing the effects of estrogen alone (E-alone) and estrogen plus progestin (E P) on coronary heart disease (CHD) as the primary outcome, hip and other fractures and colorectal cancer as secondary outcomes.
Annals of EpidemiologyThe women's health initiative dietary modification trial: overview and baseline characteristics of participants
202 Citations2003Cheryl Ritenbaugh, Ruth E. Patterson +5 more
The Dietary Modification component of the Women’s Health Initiative is a randomized controlled evaluation of a low-fat diet that is high in fruits, vegetables, and grains to reduce the risk of breast and colorectal cancer and secondarily, coronary heart disease in postmenopausal women.
Annals of EpidemiologyThe women's health initiative calcium–vitamin D trial: overview and baseline characteristics of participants
137 Citations2003Rebecca D. Jackson, Andrea Z. LaCroix +2 more
Current Opinion in LipidologyCarbohydrate-induced hypertriglyceridemia: modifying factors and implications for cardiovascular risk
121 Citations2002Marc K. Hellerstein
The present review addresses recent developments relevant to several important unresolved issues, including the type of dietary carbohydrate that is most likely to induce hypertriglyceridemia, predictors of individual susceptibility, modifiable physiologic factors that may mitigate the plasma triglyceride response, and implications of altered serum lipid profiles for atherogenic risk.
Obstetrical & Gynecological SurveyLow-Fat Dietary Pattern and Risk of Colorectal Cancer: The Women???s Health Initiative Randomized Controlled Dietary Modification Trial
119 Citations2006Shirley A.A. Beresford, Karen Johnson +45 more
Journal of the American Dietetic AssociationResults of an Adjunct Dietary Intervention Program in the Women's Health Initiative
116 Citations2002Deborah J. Bowen, CAROLYN EHRET +11 more
The results of this study indicate that a protocol based on motivational interviewing and delivered through contacts with trained dietitians is an efficacious way to further lower dietary fat intake among participants exposed to ongoing intervention.
Journal of the American Dietetic AssociationDid fat intake in the United States really decline between 1989-1991 and 1994-1996?☆☆☆★★★
75 Citations2003Prithiva Chanmugam, Joanne F. Guthrie +4 more
It is concluded that assessing trends in fat intake as a percent of energy consumption can be misleading, unless information on total energy and fat intake, in grams, is also provided.
Journal of the American Dietetic AssociationChanges in food sources of dietary fat in response to an intensive low-fat dietary intervention: Early results from the Women's Health Initiative
63 Citations2003Ruth E. Patterson, Alan R. Kristal +7 more
Data indicate that women in the Women's Health Initiative dietary change intervention made substantial changes in food choices, which can facilitate future low-fat interventions, and also offer clinical applications, by identifying foods that may be refractory to change.
Obstetrical & Gynecological SurveyLow-Fat Dietary Pattern and Risk of Invasive Breast Cancer: The Women???s Health Initiative Randomized Controlled Dietary Modification Trial
40 Citations2006Ross L. Prentice, Bette J. Caan +46 more
Among postmenopausal women, a low-fat dietary pattern did not result in a statistically significant reduction in invasive breast cancer risk over an 8.1-year average follow-up period, and the nonsignificant trends observed indicate that longer, planned, nonintervention follow- up may yield a more definitive comparison.
Journal of the American Dietetic AssociationChanges in food sources of dietary fat in response to an intensive low-fat dietary intervention: Early results from the Women's Health Initiative☆☆☆
35 Citations2003Ruth E. Patterson, Alan R. Kristal +7 more
Journal of Women s HealthTypes of Carbohydrates and Risk of Cardiovascular Disease
33 Citations2003Mark A. Pereira, Simin Liu
Recommendations to follow a diet including an abundance of fiber-rich foods in order to prevent CVD and diabetes are based on a wealth of consistent scientific evidence.
Obstetrics and GynecologyLow-Fat Dietary Pattern and Weight Change Over 7 Years: The Womenʼs Health Initiative Dietary Modification Trial
21 Citations2006
BiometricsEstimation of the Correlation Between Nutrient Intake Measures Under Restricted Sampling
9 Citations1999C. Y. Wang, Garnet L. Anderson +1 more
This paper applies likelihood‐based and multiple imputation methods to accommodate incomplete data obtained as a result of the study design of the Women's Health Initiative, and investigates robustness properties of the ML estimator analytically.