Chiral Diene as the Ligand for the Synthesis of Axially Chiral Compounds via Palladium-Catalyzed Suzuki−Miyaura Coupling Reaction
Organic LettersPublished 11 November 2010
Shu-Sheng Zhang, Zhi-Qian Wang, Ming‐Hua Xu, Guo-Qiang Lin
Citations118
SJR quartileQ1
SJR score1.24
SNIP1.03
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TL;DR
The first palladium-diene-catalyzed asymmetric Suzuki-Miyaura coupling reaction has been achieved and a number of functionalized biaryls were obtained in high yields and in moderate to high enantioselectivities.
Abstract
The first palladium-diene-catalyzed asymmetric Suzuki-Miyaura coupling reaction has been achieved. A number of functionalized biaryls were obtained in high yields and in moderate to high enantioselectivities. The existence of an ortho-formyl group greatly improves the catalyst efficiency and permits further synthetic elaborations.
Keywords
Chemistry
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