[3H] cortisol binding by young and old human liver cytosol proteins in vitro
International Journal of BiochemistryPublished 1 January 1973
Sanford S. Singer, Hiroko Itô, Gerald Litwack
Citations43
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TL;DR
There is a significant quantitative decrease in the binding proteins with old age, similar to that seen in rat and human.
Abstract
1. Corticosteroid binding proteins of liver cytosol arc similar in rat and human. 2. There is a significant quantitative decrease in the binding proteins with old age.
Keywords
MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology
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Most of the radioactive material from the liver supernatan, following injection of the isotope in vivo, consisted of at least three electrophoretically distinct, negatively charged components.
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