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Vitamin C Improves Endothelium-Dependent Vasodilation in Patients With Insulin-Dependent Diabetes Mellitus

Journal of the American College of CardiologyPublished 1 March 1998
Farris K. Timimi, Henry H. Ting, Elizabeth A. Haley, Mary-Anne Roddy, Peter Ganz, Mark A. Creager
Citations255
SJR quartileQ1
SJR score9.02
SNIP6.30

TL;DR

Vitamin C selectively restores the impaired endothelium-dependent vasodilation in the forearm resistance vessels of patients with insulin-dependent diabetes mellitus, and indicates that nitric oxide degradation by oxygen-derived free radicals contributes to abnormal vascular reactivity in humans with Diabetes mellitus.

Abstract

Vitamin C selectively restores the impaired endothelium-dependent vasodilation in the forearm resistance vessels of patients with insulin-dependent diabetes mellitus. These findings indicate that nitric oxide degradation by oxygen-derived free radicals contributes to abnormal vascular reactivity in humans with insulin-dependent diabetes mellitus.

Keywords

MedicineNursing