Basal cortisol, dexamethasone suppression of cortisol, and MHPG in adolescents after the 1988 earthquake in Armenia
American Journal of PsychiatryPublished 1 July 1996
Armen Goenjian, Rachel Yehuda, R S Pynoos, Alan M. Steinberg, Madeline Tashjian, Rong Yang
Citations312
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
The findings indicate that chronic posttraumatic stress reactions among adolescents exposed to catastrophic disaster are associated with hypothalamic-pituitary-adrenal (HPA) axis alterations and are congruent with those previously described in adults with chronic PTSD.
Abstract
The findings indicate that chronic posttraumatic stress reactions among adolescents exposed to catastrophic disaster are associated with hypothalamic-pituitary-adrenal (HPA) axis alterations. The findings are congruent with those previously described in adults with chronic PTSD. Persistent intrusion (category B) symptoms may constitute continued episodes of distress and evoke repeated physiological stress responses, which, over time, alter HPA axis function. The MHPG findings suggest that there may be diurnal changes associated with severity of posttraumatic stress symptoms.
Keywords
PsychologyNeuroscience
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