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Cardiac risk after mediastinal irradiation for Hodgkin's disease

Radiotherapy and OncologyPublished 1 January 1998
Christoph Glanzmann, Philipp A. Kaufmann, Rolf Jenni, Othmar M Hess, P Huguenin
Citations200
SJR quartileQ1
SJR score1.74
SNIP1.64

TL;DR

In patients without the usual cardiovascular risk factors the risk of serious cardiac lesions after conventionally fractionated irradiation of the mediastinum with an intermediate total dose between 30 and 40 Gy is low and the cardiac risk of the combination of this irradiation with Ct including adriamycin seems low but further long-term observation is necessary.

Abstract

In patients without the usual cardiovascular risk factors (smoking, hypertension, obesity, hypercholesterolemia, diabetes mellitus) the risk of serious cardiac lesions after conventionally fractionated irradiation of the mediastinum with an intermediate total dose between 30 and 40 Gy is low. Also the cardiac risk of the combination of this irradiation with Ct including adriamycin with a total dose between 200 and 300 mg/m2 seems low but further long-term observation is necessary.

Keywords

Medicine