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Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

Molecular and Cellular BiologyPublished 1 November 1986Open access
Bernard Mathey-Prévôt, Gary J. Nabel, Ronald Palacios, David Baltimore
Citations119
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Abstract

Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

Keywords

Agricultural and Biological SciencesMedicine