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West Nile virus: crossing the blood-brain barrier

Nature MedicinePublished 1 December 2004
Michael Diamond, Robyn S. Klein
Citations90
SJR quartileQ1
SJR score18.33
SNIP8.71

TL;DR

A study in mice traces the path of West Nile virus into the brain and finds that viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier.

Abstract

A study in mice traces the path of West Nile virus into the brain. Viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier ( pages 1366–1373 ).

Keywords

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology