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Ventilatory drive and the apnea-hypopnea index in six-to-twelve year old children

BMC Pulmonary MedicinePublished 29 April 2004Open access
Ralph F. Fregosi, Stuart F. Quan, A. Jackson, Kris L. Kaemingk, Wayne J. Morgan, Jamie Goodwin
Citations18
SJR quartileQ2
SJR score0.89
SNIP1.08
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TL;DR

Reduced hypoxic drive or resting CO2 retention while awake can explain the severity of sleep-disordered breathing in this population is uncertain, but a reduced hypoxic ventilatory drive and resting CO2 retention are associated with sleep-disordered breathing in 6–12 year old children.

Abstract

In awake children the OAHI correlates inversely with the hypoxic ventilatory drive and positively with the resting PETCO2. Whether or not diminished hypoxic drive or resting CO2 retention while awake can explain the severity of sleep-disordered breathing in this population is uncertain, but a reduced hypoxic ventilatory drive and resting CO2 retention are associated with sleep-disordered breathing in 6-12 year old children.

Keywords

MedicineNeuroscience