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New generation antipsychotics versus low-potency conventional antipsychotics: a systematic review and meta-analysis

The LancetPublished 1 May 2003
Stefan Leucht, Kristian Wahlbeck, Johannes Hamann, Werner Kissling
Citations727
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

New generation drugs were moderately more efficacious than low-potency antipsychotics, largely irrespective of the comparator doses used, and potential advantages in efficacy of the new generation drugs should be a factor in clinical treatment decisions to use these rather than conventional drugs.

Abstract

Optimum doses of low-potency conventional antipsychotics might not induce more EPS than new generation drugs. Potential advantages in efficacy of the new generation drugs should be a factor in clinical treatment decisions to use these rather than conventional drugs.

Keywords

MedicineEconomics, Econometrics and Finance