Prestimulus cortical potentials predict the performance in a saccadic distractor paradigm
Clinical NeurophysiologyPublished 1 June 2001
Stefan Everling, Allison Matthews, H. Flohr
Citations9
SJR quartileQ1
SJR score1.33
SNIP1.38
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TL;DR
It is suggested that task-specific preparatory cortical processes in the frontal lobe prior to stimulus presentation have a major influence on the performance in distractor paradigms.
Abstract
These findings suggest that task-specific preparatory cortical processes in the frontal lobe prior to stimulus presentation have a major influence on the performance in distractor paradigms.
Keywords
Neuroscience
Journal of NeurophysiologyPosterior parietal association cortex of the monkey: command functions for operations within extrapersonal space
2,069 Citations1975Vernon B. Mountcastle, James C. Lynch +3 more
A large proportion of area 5 neurons were relatively insensitive to passive joint rotations, as compared with similar neurons of the postcentral gyrus, but were driven to high rates of discharge when the same joint was rotated during an active movement of the animal.
Journal of NeurophysiologyPrimate frontal eye fields. I. Single neurons discharging before saccades
1,433 Citations1985Charles J. Bruce, Michael E. Goldberg
This continuum of visuomovement cells suggests that although visual cells are quite distinct from movement cells, the division of cell types into three classes may be only a heuristic means of describing the processing flow from visual input to eye-movement output.
Vision ResearchPrimary and secondary saccades to goals defined by instructions
1,260 Citations1978Peter Hallett
The highly idiosyncratic “anti-task” latency data can be normalized by reference to the Wheeless 2-step paradigm, and the human saccadic system is optimized for, but not restricted to, foveation.
ScienceNeural Control of Voluntary Movement Initiation
1,197 Citations1996Doug P. Hanes, Jeffrey D. Schall
Stochastic variability in the rate at which neural activity grew toward a specific and constant threshold activation level resulted in the distribution of reaction times, elucidates a specific link between motor behavior and activation of neurons in the cerebral cortex.
Journal of NeurophysiologySignal Timing Across the Macaque Visual System
1,065 Citations1998Matthew Schmolesky, Youngchang Wang +5 more
Differences in the time course of activation across the dorsal and ventral streams provide important temporal constraints on theories of visual processing.
Experimental Brain ResearchFrontal lobe lesions in man cause difficulties in suppressing reflexive glances and in generating goal-directed saccades
1,013 Citations1985Daniel Guitton, Henry A. Buchtel +1 more
The results support the view that the frontal lobes, particularly the dorsolateral region which contains the FEF and possibly the supplementary motor area contribute to the generation of complex saccadic eye-movement behaviour and in triggering the appropriate volitional movements when the goal for the movement is known but not yet visible.
Journal of NeurophysiologyParietal lobe mechanisms for directed visual attention
929 Citations1977James C. Lynch, Vernon B. Mountcastle +2 more
A total of 907 neurons of area 7 were identified in terms of their physiological properties, particularly the correlation of their activity with the oculomotor components of these behavioral acts of directed visual attention; 480 of these were located by cytoarchitectural layer.
Behavioral and Brain SciencesExpress saccades and visual attention
661 Citations1993B. Fischer, Heike Weber
It is hypothesize that an optomotor reflex is responsible for the occurrence of express saccades, one that is controlled by higher brain functions involved in disengaged visual attention and decision making and proposed a neural network as the basis for more elaborate mathematical models or computer simulations of the optom motor system in primates.
PubMedThe neurobiology of saccadic eye movements.
631 Citations1989Robert H. Wurtz, Michael E. Goldberg
NeuropsychologiaReliability and validity of some handedness questionnaire items
613 Citations1974Denis Raczkowski, James W. Kalat +1 more
Twenty-three items have been scaled for reliability and validity and for the frequency of right hand preference by predominantly left handed people and certain items are recommended for inclusion on future handedness questionnaires.
NeuropsychologiaThe antisaccade: a review of basic research and clinical studies
610 Citations1998Stefan Everling, Burkhart Fischer
What is currently known about the neural structures and processes which are involved in the performance of this task is reviewed and the potential of the antisaccade task for diagnostic purposes is evaluated.
Journal of NeuroscienceNeuronal Activity in Monkey Superior Colliculus Related to the Initiation of Saccadic Eye Movements
610 Citations1997Michael C. Dorris, Martin Paré +1 more
Analysis of neuronal activity in the superior colliculus in monkeys performing the gap paradigm provides insights into the functional mechanism of saccade initiation and may be relevant to the generation of all voluntary motor responses.
BrainCORTICAL CONTROL OF REFLEXIVE VISUALLY-GUIDED SACCADES
584 Citations1991C. Pierrot‐Deseilligny, S. Rivaud +2 more
The results suggest that the PFC is the main area in the cerebral hemisphere inhibiting reflexive visually-guided saccades, in or near the superior part of the angular gyrus.
Journal of NeuroscienceNeuronal Correlates for Preparatory Set Associated with Pro-Saccades and Anti-Saccades in the Primate Frontal Eye Field
568 Citations2000Stefan Everling, Douglas P. Munoz
Evidence for set-related activity for saccadic eye movements in single neurons in the frontal eye field in monkeys trained on a task in which they either had to look toward a visual stimulus or away from the stimulus depending on a previous instruction is reported.
Archives of NeurologyThe Neurobiology of Saccadic Eye Movements
550 Citations1990Jonathan C. Horton
This multiauthored volume, the third in a series devoted to oculomotor research, provides an excellent, comprehensive review of recent work in the field, and summarizes the neural structures involved in the generation of saccades.
Journal of NeurophysiologyRole of Frontal Eye Fields in Countermanding Saccades: Visual, Movement, and Fixation Activity
509 Citations1998Doug P. Hanes, Warren F. Patterson +1 more
Journal of NeurophysiologyFunctional properties of corticotectal neurons in the monkey's frontal eye field
436 Citations1987Mark A. Segraves, Michael E. Goldberg
The activity of identified corticotectal neurons in the frontal eye field of awake behaving rhesus monkeys was studied while the monkey performed behavioral tasks designed to test the relation of the neuron's discharge to visual and oculomotor events.
Journal of NeurophysiologyLateral Inhibitory Interactions in the Intermediate Layers of the Monkey Superior Colliculus
435 Citations1998Douglas P. Munoz, Peter J. Istvan
It is suggested that a local network of inhibitory interneurons may help shape not only the reciprocal discharge pattern of fixation and saccade neurons but also permit lateral interactions between all regions of the ipsilateral and contralateral SC.
Journal of NeurophysiologySpatial properties of visual fixation neurons in posterior parietal association cortex of the monkey
388 Citations1980H Sakata, Hidetoshi Shibutani +1 more
Even in such visually sensitive VF neurons, their positional selectivity depended mainly on eye position, suggesting that visual stimuli in the surroundings have some excitatory effects on these neurons.
Progress in NeurobiologyThe microscopic anatomy and physiology of the mammalian saccadic system
365 Citations1996Adonis Moschovakis, C. A. Scudder +1 more
This review focuses on the neural network that generates the rapid movements of the eyes that are called saccades, and several computational models of the saccadic system have been proposed in an attempt to understand the functional significance of the simultaneous operation of these loops.
NatureAntisaccade performance predicted by neuronal activity in the supplementary eye field
337 Citations1997Madeleine Schlag-Rey, Nelly Amador +2 more
It is shown, using recordings from the supplementary eye field (a frontal cortex oculomotor centre) in monkeys, that visual and movement neurons retain the same spatial selectivity across randomly mixed pro- and antisaccade trials, suggesting a mechanism through which voluntary antisaccades commands can override reflexive glances.
Journal of NeurophysiologyA neural correlate for the gap effect on saccadic reaction times in monkey
322 Citations1995Michael C. Dorris, Douglas P. Munoz
It is proposed that the activity of fixation cells in the monkey superior colliculus provide a neural correlate of the gap effect, which weakens the powerful state of inhibition which they normally exert upon the saccade generating system, allowing targets to be acquired at shorter reaction times.
BrainCortical control of saccades and fixation in man A PET study
316 Citations1994Tim Anderson, I. H. Jenkins +4 more
It is concluded that FEF and PPC are associated with the generation of both reflexive and remembered saccades, with SMA additionally involved during remembered sACCs, which are mediated by prefrontal cortex.
Vision ResearchThe predictability of saccadic latency in a novel voluntary oculomotor task
295 Citations1980Peter Hallett, Beth Adams
A simple model is applied to the “anti” task, the Wheeless 2-step task and forewarning, which shows great flexibility in its choice of goal, but is rather stereotyped in timing.
PubMedDischarge of frontal eye field neurons during saccadic and following eye movements in unanesthetized monkeys.
288 Citations1968Emilio Bizzi
Results indicate that cortical neurons have patterns of discharge distinctly related either to saccadic or to pursuit movements, in line with the view that these two different types of eye movement are generated by distinct neuronal mechanisms.
Proceedings of the National Academy of SciencesMemory fields of neurons in the primate prefrontal cortex
283 Citations1998Gregor Rainer, Wael F. Asaad +1 more
Results indicate that PF neurons can simultaneously convey precise location and object information and thus may play a role in constructing a unified representation of a visual scene.
Experimental Brain ResearchDischarge of frontal eye field neurons during saccadic and following eye movements in unanesthetized monkeys
279 Citations1968Emilio Bizzi
Biological PsychiatryDisturbances of voluntary control of saccadic eye movements in schizophrenic patients
266 Citations1988Junko Fukushima, Kikuro Fukushima +4 more
The results indicate that many schizophrenics show difficulties in voluntary control of saccades, suggesting a dysfunction of the frontal cortex.
Experimental Brain ResearchCharacteristics of ?anti? saccades in man
247 Citations1992B. Fischer, Heike Weber
The introduction of the gap clearly decreases the reaction times of the anti saccades, providing further evidence for the existence of a reflex-like pathway connecting the retina to the oculomotor nuclei mediating the Express saccade.
Journal of NeurophysiologyActivity of monkey frontal eye field neurons projecting to oculomotor regions of the pons
213 Citations1992Mark A. Segraves
The present study confirms and extends the results of previous work, with the use of retrograde and anterograde tracers, demonstrating direct projections from the frontal eye field to the pons, suggesting that there is at least one additional neuron between frontal eyeField neurons and burst neurons in the PPRF.
Journal of NeurophysiologyComparison of the Discharge Characteristics of Brain Stem Omnipause Neurons and Superior Colliculus Fixation Neurons in Monkey: Implications for Control of Fixation and Saccade Behavior
206 Citations1998Stefan Everling, Martin Paré +2 more
Comparisons of the role and relationship of SCFNs and OPNs with respect to both fixation behavior and saccade generation reveal differences in the discharge properties that are irreconcilable with the hypothesis that the discharge pattern of OPN's reflects simply the excitatory input from SC FNs.
Journal of NeurophysiologyReflex Suppression in the Anti-Saccade Task Is Dependent on Prestimulus Neural Processes
200 Citations1998Stefan Everling, Michael C. Dorris +1 more
It is found that the level and distribution of prestimulus activity of buildup neurons in the SC was highly predictive of whether a correct response or an error occurred and suggest that the successful suppression of reflexive saccades is dependent on prestIMulus neural processes in theSC.
Journal of NeurophysiologyParticipation of prefrontal neurons in the preparation of visually guided eye movements in the rhesus monkey
184 Citations1989R. Boch, Michael E. Goldberg
Journal of NeurophysiologyActivity of visuomotor burst neurons in the superior colliculus accompanying express saccades
165 Citations1996Jay A. Edelman, E.L. Keller
Brain ResearchPrefrontal neuronal activity during gazing at a light spot in the monkey
158 Citations1977Hisao Suzuki, Masao Azuma
The activation of the G neurons was little influenced by stimulus parameters, such as the size, intensity and position of the light spot, however, it was dependent on behavioral state of the animal: error trials with delayed key-release showed a weak activation while extinction procedure induced enhanced activation in the initial several trials.
Journal of NeurophysiologySuppression of Task-Related Saccades by Electrical Stimulation in the Primate's Frontal Eye Field
137 Citations1997Douglas D. Burman, Charles J. Bruce
It is hypothesized that saccades could be suppressed both through local FEF interactions and through FEF projections to subcortical regions involved in maintaining fixation and shown that the primate FEF can help orchestrate saccadic eye movements by suppressing inappropriate saccade vectors.
Journal of NeurophysiologyPhysiological correlate of fixation disengagement in the primate's frontal eye field
133 Citations1994Elisa C. Dias, Charles J. Bruce
The recorded from the frontal eye field of rhesus monkeys while they performed the gap task in which the fixation point disappears 200 ms before the appearance of the peripheral saccadic target greatly reducing saccade latency ("gap effect"), led to the discovery of an increase a fixation-disengagement discharge (FDD).
Journal of NeuroscienceThe Influence of Auditory and Visual Distractors on Human Orienting Gaze Shifts
123 Citations1996Brian D. Corneil, Douglas P. Munoz
Subjects adopted a state of motor readiness that reflected the unique demands of target selection in each experiment and that this state modulated the influences of the irrelevant cue on the target, revealing patterns of influence unique to either visual or auditory irrelevant cues that occurred regardless of the modality of the target.
NeuropsychologiaAttention and oculomotor control: A high-density ERP study of the gap effect
98 Citations1997Gergely Csibra, Mark H. Johnson +1 more
Three neural correlates of the gap effect are observed: a prefrontal positivity that precedes the target presentation which may reflect specific preparatory processes, an enhancement of the early cortical visual responses to the peripheral target in the gap trials, and a prolongation of parietal activity in the overlap trials relative to the gap Trials prior to the saccade execution.
Journal of NeurophysiologyVisualization of the Information Flow Through Human Oculomotor Cortical Regions by Transcranial Magnetic Stimulation
96 Citations1998Yasuo Terao, Hideki Fukuda +8 more
The figure-eight shaped coil technique provides a useful method not only for detecting the topography of cortical regions active during saccadic eye movement, but also for constructing a physiological map to visualize the temporal evolution of functional activities in the relevant cortical regions.
Experimental Brain ResearchThe dorsomedial frontal cortex of the macaca monkey: fixation and saccade-related activity
91 Citations1992Leopoldo Bon, Cristina Lucchetti
The properties of neurons that showed activity related to visual fixation and saccadic eye movement are described and it is proposed that their involvement in arm-eye-head motor-planning rests primarily in targeting the goal of the movement.
Experimental Brain ResearchSupplementary eye field: influence of eye position on neural signals of fixation
88 Citations1992J. Schlag, Madeleine Schlag-Rey +1 more
Two patterns of unit activity were observed while the animals fixated photic stimuli, indicative of eye eccentricity in orbit and a monotonically varying firing rate dependent on the eye orientation along a particular axis.
Experimental Brain ResearchEvent-related potentials associated with correct and incorrect responses in a cued antisaccade task
88 Citations1998Stefan Everling, A. Spantekow +2 more
The view that the supplementary eye fields participate in the inhibition of incorrect saccades in a cued antisaccade task and that the parietal cortex participates in generating a neural representation of the visual stimulus in the hemifield ipsilateral to the stimulus before generating a motor response are supported.
Experimental Brain ResearchEvidence for interactions between target selection and visual fixation for saccade generation in humans
60 Citations1995DouglasP. Munoz, Brian D. Corneil
The results support a recent hypothesis suggesting that the processes of disengaging active visual fixation and selecting a new saccade target are interrelated and arise, at least in part, from a change of activity within the superior colliculus.
Vision ResearchDifferential effects of non-target stimuli on the occurrence of express saccades in man
55 Citations1994Heike Weber, Burkhart Fischer
The effect of competing non-target stimuli (distractors) presented together with a target for saccades was investigated with special emphasis on saccadic reaction time and depended mainly on their position in the visual field.
International Journal of PsychophysiologyResponse latencies and event-related potentials during the gap paradigm using saccadic responses in human subjects
27 Citations1996Carlos M. Gómez, Mercedes Atienza +2 more
The results suggest that fast regular saccades during the gap paradigm occur by a priming of premotor and motor frontal circuits indexed by the recorded negativity during thegap paradigm.
Experimental Brain ResearchCortical potentials during the gap prior to express saccades and fast regular saccades
23 Citations1996S. Everting, P. Krappmann +2 more
It is hypothesized that fast regular saccades are the result of an increased readiness signal, while express saccade are the results of specific preparatory processes.
Neuroscience LettersCortical potentials during gap and non-gap paradigms using manual responses in humans
20 Citations1995Carlos M. Gómez, Mercedes Atienza +3 more
The results suggest that the gap promotes the speeding of the response by a cortical priming.
Experimental Brain ResearchEvent-related potentials and saccadic reaction times: effects of fixation point offset or change
19 Citations1999A. Spantekow, P. Krappmann +2 more
The findings of shorter SRTs during the gap task than the warning task, however, suggest that the gap has an additional effect that probably depends on subcortical mechanisms.