Survival in Amyotrophic Lateral Sclerosis
Archives of NeurologyPublished 1 January 1994
Evelyn McDonald
Citations194
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Patients with psychological distress had a greater risk of mortality and greater likelihood of dying in any given time period than those with psychological well-being, and adjusting for confounding factors, psychological status is strongly related to outcome in amyotrophic lateral sclerosis.
Abstract
Adjusting for confounding factors, psychological status is strongly related to outcome in amyotrophic lateral sclerosis. Further studies on psychological status should be done to confirm its prognostic value.
Keywords
Social SciencesMedicine
Springer series in statisticsNonparametric Estimation from Incomplete Observations
45,533 Citations1992Edward L. Kaplan, Paul Meier
Journal of Health and Social BehaviorA Global Measure of Perceived Stress
32,415 Citations1983Sheldon Cohen, Tom Kamarck +1 more
The Perceived Stress Scale showed adequate reliability and, as predicted, was correlated with life-event scores, depressive and physical symptomatology, utilization of health services, social anxiety, and smoking-reduction maintenance and was a better predictor of the outcome in question than were life- event scores.
Journal of Consulting and Clinical PsychologyThe measurement of pessimism: The Hopelessness Scale.
5,392 Citations1974Aaron T. Beck, Arlene Weissman +2 more
A scale designed to quantify hopelessness was administered to several diverse samples of patients to assess its psychometric properties and was found to have a high degree of internal consistency and showed a relatively high correlation with the clinical ratings of hopelessness and other self-administered measures of despair.
Journal of Personality and Social PsychologyThe revised UCLA Loneliness Scale: Concurrent and discriminant validity evidence.
3,604 Citations1980Daniel W. Russell, Letitia Anne Peplau +1 more
Two studies provide methodological refinement in the measurement of loneliness, demonstrating that although loneliness is correlated with measures of negative affect, social risk taking, and affiliative tendencies, it is nonetheless a distinct psychological experience.
The LancetEFFECT OF PSYCHOSOCIAL TREATMENT ON SURVIVAL OF PATIENTS WITH METASTATIC BREAST CANCER
2,368 Citations1989David Spiegel, H C Kraemer +2 more
The effect of psychosocial intervention on time of survival of 86 patients with metastatic breast cancer was studied prospectively and survival plots indicated that divergence in survival began at 20 months after entry, or 8 months after intervention ended.
Journal of Social and Personal RelationshipsA Brief Measure of Social Support: Practical and Theoretical Implications
1,994 Citations1987Irwin G. Sarason, Barbara R. Sarason +2 more
New England Journal of MedicinePsychological Stress and Susceptibility to the Common Cold
1,714 Citations1991Sheldon Cohen, D. A. J. Tyrrell +1 more
Psychological stress was associated in a dose-response manner with an increased risk of acute infectious respiratory illness, and this risk was attributable to increased rates of infection rather than to an increased frequency of symptoms after infection.
Journal of Personality and Social PsychologyLong-term effects of a control-relevant intervention with the institutionalized aged.
593 Citations1977Judith Rodin, Ellen J. Langer
JAMAPsychological Coping Mechanisms and Survival Time in Metastatic Breast Cancer
489 Citations1979Leonard R. Derogatis
The long-term survivors were more symptomatic overall, with particular elevations on measures of anxiety and alienation, and substantially higher levels of dysphoric mood (eg, depression, guilt) than the short- term survivors.
Journal of Behavioral MedicineRaw versus relative scores in the assessment of coping strategies
375 Citations1987Peter P. Vitaliano, Roland D. Maiuro +2 more
It was hypothesized that the maladaptive status of the psychiatric outpatients would report more emotion-focused strategies and less problem-focused coping than the nonclinical samples and that these differences would be better observed using relative rather than raw scores.
Annals of NeurologyAmyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management
370 Citations1985Rup Tandan, Walter G. Bradley
New England Journal of MedicineType a Behavior and Mortality from Coronary Heart Disease
360 Citations1988David R. Ragland, Richard Brand
The results do indicate that patients with CHD and a Type A behavior pattern are not at increased risk for subsequent CHD mortality, and lower mortality among Type A subjects occurred in both younger and older subgroups.
New England Journal of MedicinePsychosocial Correlates of Survival in Advanced Malignant Disease?
359 Citations1985Barrie R. Cassileth, Edward J. Lusk +3 more
Social and psychological factors individually or in combination do not influence the length of survival or the time to relapse after a diagnosis of cancer, and the biology of the disease appears to predominate and to override the potential influence of life-style and psychosocial variables once the disease process is established.
Psychosomatic MedicinePsychological Depression and 17-Year Risk of Death from Cancer1
322 Citations1981Richard B. Shekelle, William J. Raynor +6 more
Psychological depression was associated with a twofold increase in odds of death from cancer during 17 years of follow‐up, and persisted after adjustment for age, cigarette smoking, use of alcohol, family history of cancer, and occupational status, and was apparently not specific to any particular site or type of cancer.
Journal of PersonalityPsychobiological Factors Predicting the Course of Breast Cancer
250 Citations1987Mogens R. Jensen
JAMADepression as a Risk for Cancer Morbidity and Mortality in a Nationally Representative Sample
248 Citations1989Alan B. Zonderman
The results call into question the causal connection between depressive symptoms and cancer morbidity and mortality.
Journal of Psychosomatic ResearchThe relationship of psychosocial factors to prognostic indicators in cutaneous malignant melanoma
215 Citations1985Lydia Temoshok, Bruce W. Heller +5 more
NeuroepidemiologyAmyotrophic Lateral Sclerosis Severity Scale
213 Citations1989Allen D. Hıllel, Robert M. Miller +4 more
The amyotrophic lateral sclerosis severity scale has been shown to have an average estimated reliability coefficient of 0.95 between examiners and speech ratings were correlated greater than 0.80 for objective speech measures.
New England Journal of MedicineType A Behavior and Survival after Acute Myocardial Infarction
203 Citations1985Robert B. Case, Stanley S. Heller +2 more
There was no relation between Type A behavior and the long-term outcome of acute myocardial infarction and the multivariate survivorship analyses found.
Journal of Psychosomatic ResearchThe role of stress, social support and age in survival from breast cancer
198 Citations1983Donna P. Funch, James R. Marshall
Using the entire sample, stage of cancer at diagnosis was the best predictor of survival, however, when women aged 46-60 were eliminated from the analysis, stress and social involvement accounted for twice as much variance in survival as stage.
Archives of NeurologyAmyotrophic Lateral Sclerosis
174 Citations1978Arthur D. Rosen
The clinical diagnosis of amyotrophic lateral sclerosis was identified in 668 patients who were followed up for periods up to three years and the spinal form was associated with a threefold better five-year survival than the bulbar form.
Psychosomatic MedicinePsychological Factors in the Prognosis of Malignant Melanoma: A Prospective Study*
171 Citations1979Nicholas Rogentine, Daniël P. van Kammen +5 more
A role for psychological factors in the one year prognosis of this malignancy is suggested and the melanoma adjustment score was independent of known biological prognostic factors, which did not predict 1 year survival.
Neurologic ClinicsAmyotrophic Lateral Sclerosis: Its Natural History
170 Citations1987James T. Caroscio, Michael Mulvihill +2 more
There seems to be a pattern of progression of ALS signs and symptoms based on area of onset with LLE involvement tending to follow RLE weakness, LUE weakness following RUE onset, and RUE involvement following next in patients whose onset is bulbar.
Psychosomatic MedicineThe relationship of depression to survival in chronic renal failure.
162 Citations1986Howard J. Burton, S.A. Kline +2 more
It is suggested that demographic and psychosocial factors may be more important than physiologic variables in determination of survival on home dialysis in patients with chronic renal failure.
Radiotherapy and OncologyPrognostic factors for patients with inoperable non-small cell lung cancer, limited disease
158 Citations1989Stein Kaasa, Arne Mastekaasa +1 more
In a prospective controlled clinical trial, 102 patients with inoperable non-small cell lung cancer, limited disease, stage II and III were treated with combination chemotherapy, cisplatin 70 mg/m2 i.v. on day one and etoposide 200 mg/ m2 orally on days 2 and 3, and subjective variables, general symptoms and psychosocial well-being were shown to have the best predictive value for the patients' survival.
Journal of Psychosomatic ResearchPatterns of expression of anger and their psychological correlates in women with breast cancer
154 Citations1981Tina Morris, Steven Greer +2 more
Taped transcripts of interviews, independently rated, using a revised anger rating scale, demonstrated a significant difference between patients with benign breast disease and those with breast cancer in expression of anger, suggesting that cancer patients are more stressed by impending biopsy.
Journal of Chronic DiseasesThe prognostic significance of psychosocial factors in women with breast cancer
152 Citations1987T. Gregory Hislop, Nancy E. Waxler +3 more
A self-administered questionnaire which measured 16 psychosocial variables supported the prognostic importance of the social emotional network in breast cancer patients.
Annals of NeurologyAmyotrophic leteral sclerosis: Part 2. Etiopathogenesis
144 Citations1985Rup Tandan, Walter G. Bradley
The pathogenesis of the motor neuronal degeneration in amyotrophic lateral sclerosis (ALS) is unclear, though several possible etiological factors are currently being investigated.
Journal of Psychosomatic ResearchDo psychological factors predict survival in breast cancer?
143 Citations1989Christine Dean, Paul G. Surtees
Those who were assessed three months after operation as coping by using a strategy of denial had a better chance of remaining recurrence-free than those women employing other coping strategies; this finding must be viewed with reservation because of the inherent difficulties in measuring coping strategies.
Journal of Clinical PsychologyFactor structure, construct validity and reliability of the seeking of noetic goals (SONG) and purpose in life (PIL) tests
131 Citations1979Gary T. Reker, J. Bradley Cousins
Journal of Clinical OncologyPsychogenic factors in predicting survival of breast cancer patients.
130 Citations1987Robert N. Jamison, Thomas G. Burish +1 more
The data suggest that, for breast cancer patients with metastatic disease, disease-related variables probably outweigh the influence of select psychosocial factors in determining length of survival.
Psychosomatic MedicineThe Affect of Hopelessness and the Development of Cancer
129 Citations1966Arthur H. Schmale, Howard P. Iker
The so‐called predisposition as well as psychological factors found by other investigators to differentiate women with cervical cancer from women with other forms of cancer or “no cancer” did not differentiate between the subjects in the present study.
Journal of Clinical OncologyPsychosocial correlates of cancer survival: a subsequent report 3 to 8 years after cancer diagnosis.
125 Citations1988Barrie R. Cassileth, William P. Walsh +1 more
In a previously reported prospective investigation of 359 patients with newly diagnosed malignant diseases, no relationship between clinical outcome and any psychosocial factor studied was found.
NeuroepidemiologyFollow-Up Study on Amyotrophic Lateral Sclerosis in Rochester, Minn., 1925 through 1984
124 Citations1986Sohei Yoshida, Donald W. Mulder +3 more
The incidence, secular trend and survivorship of amyotrophic lateral sclerosis in the Rochester, Minn., population has been investigated over a 60-year period, 1925 through 1984, and younger patients had a better prognosis than patients with an advanced age at onset.
PubMedPatient resistance and prognosis in amyotrophic lateral sclerosis.
118 Citations1976Mulder Dw, Howard Fm
It is assumption, based on data as well as on additional clinical observations, that many patients with amyotrophic lateral sclerosis live for longer than 5 years and, rarely, they may have remissions of their illness.
Psychosomatic MedicinePsychological Function in Individuals with Amyotrophic Lateral Sclerosis (ALS)
65 Citations1970Walter A. Brown, Peter S. Mueller
It is suggested that an individual's response to an incapacitating illness reflects and perhaps can be predicted from his premorbid life style and the role of unresolved, covert depression on the course of ALS remains to be demonstrated.
Psychosomatic MedicinePsychological Characteristics of Patients with Amyotrophic Lateral Sclerosis (ALS)
63 Citations1977Jeffrey L. Houpt, Brian S. Gould +1 more
Although dysphoria was frequently found in ALS patients, only 22% demonstrated clinical depressive syndromes, and ALS patients were not found to have a more internal locus of control, or to use denial as a defense more than a group of patients with inoperable neoplastic disease.
Neurologic ClinicsNeuropsychological Perspectives in Amyotrophic Lateral Sclerosis
62 Citations1987George K. Montgomery, Lynelle M. Erickson
An analysis of trends in psychological adjustment and in the perception of physical capability over the course of a pilot clinical trial is described.
Journal of Clinical EpidemiologyThe effect of psychosocial factors on lung cancer mortality at one year
41 Citations1988Kathleen M. Stavraky, Allan Donner +2 more
The following psychological variables were found to increase the odds of death from lung cancer among males and females combined at one year after diagnosis: a high need for one aspect of social support, a reserved personality and the extremes of the personality trait soberness vs enthusiasm.
Journal of the Neurological SciencesMotor neuron disease in the province of Turin, Italy, 1966–1980
37 Citations1984Paolo Mortara, Adriano Chiò +3 more
A population based survival analysis of all incident cases of motor neuron disease in the province of Turin, Italy, during the period 1966-1980 showed both life-tables showed a similar pattern with a rapidly fatal outcome in the first 3 years after diagnosis and a slower death rate in the following years.
Archives of NeurologyIs There a Characteristic Personality Profile in Amyotrophic Lateral Sclerosis?
33 Citations1978Pamela K. Peters
A comparison of the Minnesota Multiphasic Personality Inventory profiles of 21 men and 17 women who had amyotrophic lateral sclerosis with the profiles of 50,500 general medical patients showed no marked deviations.
Health PsychologyPsychological aspects of multiple sclerosis and its treatment: Toward a biopsychosocial perspective.
32 Citations1984Cal VanderPlate
NeuroepidemiologyPsychologic and Adaptational Difficulties Anteceding Amyotrophic Lateral Sclerosis: Rochester, Minnesota, 1925–1987
5 Citations1991Carmel Armon, Leonard T. Kurland +3 more
No man in whom ALS developed had a record of mild antecedent difficulties alone, whereas 3 would have been expected (p = 0.024), and the proportions of long-standing or serious conditions were comparable in all four groups.
