Electrophysiology of adult rat facial motoneurones: the effects of serotonin (5-HT) in a novel in vitro brainstem slice
Journal of Neuroscience MethodsPublished 1 May 1989
P.M. Larkman, Nicholas J. Penington, John Kelly
Citations44
SJR quartileQ3
SJR score0.73
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TL;DR
A novel brainstem slice of the adult rat containing the facial motor nucleus (FMN) is described, indicating that they display several passive and active properties seen in other rat cranial and spinal motoneurones.
Abstract
Studies of adult rat motoneurones using in vitro slice preparations are rare. We here describe a novel brainstem slice of the adult rat containing the facial motor nucleus (FMN). Data obtained for facial motoneurones (FM) by intracellular recording indicate that they display several passive and active properties seen in other rat cranial and spinal motoneurones. Bath application of serotonin (5-HT) evokes a reversible depolarization of FMs which is associated with an increase in input resistance due to a reduction in potassium permeability. This effect is unaffected by tetrodotoxin indicating a postsynaptic site of action.
Keywords
NeuroscienceBiochemistry, Genetics and Molecular Biology
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