Functions of afferents in cardiovascular sympathetic nerves
Journal of the Autonomic Nervous SystemPublished 1 April 1981
Alberto Malliani, Federico Lombardi, Massimo Pagani
Citations37
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
This paper contains data and discussion of the role of afferents in the sympathetic trunks from the cardiovascular complex that evoke autonomic reflex action. A description is given of these cardiovascular reflexes induced by afferents of the sympathetic trunks in neurally intact as well as spinal animals. A positive feedback hypothesis is also proposed.
Keywords
Medicine
The American Journal of Cardiology“Variant” angina: One aspect of a continuous spectrum of vasospastic myocardial ischemia
939 Citations1978Attilio Maseri, Silva Severi +8 more
Angiography in all 37 patients studied during angina revealed a severe coronary vasospasm involving vessels with extremely variable extent of atherosclerosis, which may evolve into acute myocardial infarction and sudden death.
BMJAutonomic Disturbance at Onset of Acute Myocardial Infarction
419 Citations1972S W Webb, A.A.J. Adgey +1 more
The high incidence of sudden death in the acute phase of a coronary attack probably results from the electrical imbalance caused by autonomic disturbance, and this disturbance must be taken into account in any prophylactic regimen against the lethal early ventricular dysrhythmias.
The Journal of PhysiologyNervous activity of afferent cardiac sympathetic fibres with atrial and ventricular endings
288 Citations1973Alberto Malliani, G Recordati +1 more
The electrical activity of single afferent cardiac fibres isolated from the third and fourth left thoracic sympathetic rami communicantes of anaesthetized cats recorded in Fig. 1.1.
Circulation ResearchA Cardiocardiac Sympathovagal Reflex in the Cat
264 Citations1973Peter J. Schwartz, Massimo Pagani +3 more
Convergence of afferent fibers in the vagi and the cardiac sympathetic nerves on the same cardiac vagal and cardiac sympathetic postganglionic neurons was demonstrated and Convergence from carotid sinus baroreceptors was observed.
The Journal of PhysiologySpinal sympathetic reflexes initiated by coronary receptors
210 Citations1971Arthur Brown, Alberto Malliani
The main left coronary artery of vagotomized spinal cats was perfused at different flows and pressures and the changes in pressure were limited to the coronary bed.
Cardiovascular ResearchAn excitatory nociceptive cardiac reflex elicited by bradykinin and potentiated by prostaglandins and myocardial ischaemia
141 Citations1976J Staszewska-Barczak, S. H. Ferreira +1 more
Bradykinin and prostaglandins acting in concert are the natural stimulus for excitation of the sensory receptors signalling the pain of myocardial ischaemia and are the mechanism subserving the cardiovascular events which accompany anginal attacks.
Progress in NeurobiologyCentral neural regulation of heart and blood vessels in mammals
117 Citations1975F. R. Calaresu, A.A. Faiers +1 more
Circulation ResearchSpinal Sympathetic Cardiocardiac Reflexes
105 Citations1972Alberto Malliani, D. F. Peterson +2 more
The first demonstration of a cardiocardiac reflex which can be mediated entirely by the spinal cord is demonstrated, which is independent of changes in heart rate, preload, or afterload.
Circulation ResearchStimulation by bradykinin of afferent vagal C-fibers with chemosensitive endings in the heart and aorta of the dog.
103 Citations1980Marc P. Kaufman, David G. Baker +2 more
It is suggested thatChemosensitive vagal C-fibers with chemosensitive endings in the left ventricle, left atrium, and aorta were stimulated by bradykinin and are responsible for the reflex decreases in heart rate and blood pressure elicited by bradaykinin.
American Journal of Physiology-Legacy ContentEffect of dorsal root section on the arrhythmias associated with coronary occlusion
83 Citations1976Schwartz Pj, R. D. Foreman +2 more
Dorsal root section reduces the number of ectopic beats associated with short-lasting coronary artery occlusions and that the most likely mechanism is the interruption of the cardiocardiac sympathetic reflex which depends upon afferent fibers running through the dorsal roots.
CirculationDirect Arterial Pressure and the Electrocardiogram in Unrestricted Patients with Angina Pectoris
77 Citations1973William A. Littler, A. J. Honour +2 more
The Journal of PhysiologyAfferent sympathetic unmyelinated fibres with left ventricular endings in cats.
75 Citations1979Rosangela Casati, Federico Lombardi +1 more
These spontaneously active ventricular receptors with unmyelinated nerve fibres participate in the transmission of the continuous impulse activity which from the cardiovascular system reaches the spinal cord through the sympathetic nerves and which is likely to contribute to the neural control of circulation.
Brain ResearchReflex responses of sympathetic preganglionic neurones initiated by different cardiovascular receptors in spinal animals
72 Citations1974Massimo Pagani, Peter J. Schwartz +3 more
The data demonstrate that both specificity and convergence regulate cardiovascular sympathetic spinal reflexes.
Japanese Heart JournalDistribution and Responses of the Cardiac Sympathetic Receptors to Mechanically Induced Circulatory Changes
60 Citations1969Hideo UEDA, Yasumi Uchida +1 more
It was concluded that the afferent sympathetic fibers originated from the receptors in the left or right ventricle traveled respectively in theleft or right upper thoracic white rami and that the cardiac receptors which are considered to participate in pain sensibility were activated by mechanically induced circulatory alterations.
Brain ResearchSpinal cardiovascular reflexes
54 Citations1975Alberto Malliani, Federico Lombardi +3 more
The American Journal of CardiologyPositive feedback sympathetic reflexes and hypertension
45 Citations1979Alberto Malliani, Massimo Pagani +1 more
A pressor reflex that can be elicited from the thoracic aorta in conscious dogs is described, which results in an increase in arterial blood pressure because of increased sympathetic outflow to the heart and blood vessels.
The Journal of PhysiologyAfferent sympathetic nerve fibres with aortic endings.
42 Citations1976Alberto Malliani, M. Pagani
In vivo and post mortem studies showed that these mechanoreceptors had an impulse activity which rapidly adapted during sustained stimuli, and they thus seem to signal pulsatile aortic stretch.
Circulation ResearchReflex Hemodynamic Responses Initiated from the Thoracic Aorta
42 Citations1974Franco Lioy, Alberto Malliani +3 more
It is concluded that stretch of the thoracic aorta induced an increase in sympathetic activity affecting the heart, the peripheral vessels, and, probably, the adrenal glands through a spinal reflex.
Experimental Biology and MedicineAcute Cardiovascular Consequences of Anterior Descending Coronary Artery Occlusion in Unanesthetized Monkey
39 Citations1978David C. Randall, David M. Hasson +1 more
Anatomical and physiological characteristics of the non-human primate suggest that these animals provide attractive models for experimental study of anterior MI.
American Journal of Physiology-Legacy ContentReflex sympathetic changes in aortic diastolic pressure-diameter relationship
39 Citations1975M. Pagani, Schwartz Pj +2 more
Reflex control of the thoracic aorta may be involved in cardioaortic coupling and may influence the sensitivity of aortic mechanoreceptors.
The Journal of PhysiologyAfferent fibres from pulmonary arterial baroreceptors in the left cardiac sympathetic nerve of the cat
37 Citations1974Kosuke Nishi, M Sakanashi +1 more
Afferent discharges were recorded from the left cardiac sympathetic nerve or the third sympathetic ramus communicans of anaesthetized cats of anaesthetic cats.
American Journal of Physiology-Heart and Circulatory PhysiologyContrasting reflexes evoked by chemical activation of cardiac afferent nerves
33 Citations1980Katja Reimann, Lynne C. Weaver
Cardiac sympathetic afferent neurons can have significant excitatory influences on the cardiovascular system in spite of opposition by inhibitory afferent groups, as illustrated in chloralose-anesthetized, vagotomized, sinoaortic-denervated cats.
Brain ResearchNervous activity of afferent sympathetic fibers innervating the pulmonary veins
25 Citations1976Federico Lombardi, Alberto Malliani +1 more
