Absence of hepatitis C virus transmission in a prospective cohort of heterosexual serodiscordant couples
Sexually Transmitted InfectionsPublished 1 April 2003Open access
B. Marincovich
Citations123
SJR quartileQ1
SJR score1.02
SNIP1.06
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TL;DR
These results are consistent with a low or null transmissibility of HCV in heterosexual relations, even when the index case is HIV co-infected.
Abstract
These results are consistent with a low or null transmissibility of HCV in heterosexual relations, even when the index case is HIV co-infected.
Keywords
Medicine
Annals of Internal MedicineHeterosexual Co-transmission of Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV)
305 Citations1991M. Elaine Eyster, Harrison Alter +4 more
The higher prevalence of HCV in female sexual partners of men with hemophilia than in blood donor and other low-risk groups suggests that there is a low level of sexual transmission.
The LancetDetection of hepatitis C virus in the semen of infected men
170 Citations2000Marianne Leruez‐Ville, J.-M. Kunstmann +3 more
Seminal viral loads were low, but the semen could be infectious and the role of sexual transmission in the spread of HCV infection should not be underestimated.
PubMedSexual transmission of the hepatitis C virus and efficacy of prophylaxis with intramuscular immune serum globulin. A randomized controlled trial.
112 Citations1997M Piazza, Luciano Sagliocca +10 more
Archives of Internal MedicineSexual Transmission of the Hepatitis C Virus and Efficacy of Prophylaxis With Intramuscular Immune Serum Globulin
106 Citations1997Marcello Piazza
The risk of sexual transmission of hepatitis C and the value of prophylaxis with periodic intramuscular immune serum globulin administration are estimated and hyperimmune anti-HCV immune serum Globulin should be prepared from blood testing positive for antibodies to HCV, which is currently discarded.
PubMedLack of evidence for the heterosexual transmission of hepatitis C.
101 Citations1992Stuart C. Gordon, A H Patel +3 more
It is concluded that heterosexual transmission of hepatitis C is extremely uncommon, despite frequent and unprotected sexual intercourse.
Journal of InfectionAbsence of hepatitis C virus transmission but frequent transmission of HIV-1 from sexual contact with doubly-infected individuals
88 Citations1997R. Wyld, J R Robertson +4 more
Findings support the evidence of others that HCV is only rarely transmitted by sexual intercourse in heterosexual relationships and that HIV is not a co-factor for HCV transmission.
Sexually Transmitted InfectionsSexual transmission of hepatitis C virus infection
88 Citations1998G Rooney, Richard Gilson
Evidence for sexual transmission is provided by several types of study including prevalence studies in groups at risk of other STDs, investigation of cases identified from surveillance reports, and cross sectional and longitudinal partner studies.
Sexually Transmitted InfectionsHepatitis C virus infection in a large cohort of homosexually active men: independent associations with HIV-1 infection and injecting drug use but not sexual behaviour.
82 Citations1996Neil Bodsworth, Philip Cunningham +2 more
IDU was the major behavioural risk factor for HCV infection and its association with human immunodeficiency virus type 1 (HIV-1) infection and other STDs, number of sexual partners, sexual practices and recreational drug use.
The American Journal of GastroenterologyHepatitis C virus infection in spouses: sexual transmission or common exposure to the same risk factors?
71 Citations2001Tommaso Stroffolini, U. Lorenzoni +3 more
The findings that the same genotype was detected for both partners in relatively few couples, and that a history of parenteral exposure was an independent predictor of HCV positivity, suggest that the risk of sexual transmission is low.
Journal of Internal MedicineHeterosexual transmission of hepatitis C virus and the possible role of coexistent human immunodeficiency virus infection in the index case: A multicentre study of 423 pairings
67 Citations1994Bruno Perelli Soto, Luı́s Rodrigo +11 more
The role that sexual transmission plays in the spread of hepatitis C virus (HCV) infection is defined and the influence of coexistent human immunodeficiency virus (HIV) infection on this mode of transmission is examined.
Journal of Viral HepatitisSpread of hepatitis C virus infection within families
60 Citations1998N. Caporaso, Antonio Ascione +1 more
It is suggested that sexual transmission does not seem to play a role in the intrafamilial spread of HCV infection, and age greater than 45 years and any parenteral exposure were the only independent predictors of the likelihood of anti‐HCV positivity among household contacts.
Journal of Gastroenterology and HepatologyLow incidence of hepatitis C virus transmission between spouses: A prospective study
59 Citations2000Jia‐Horng Kao, Chun‐Jen Liu +4 more
QJMLack of evidence for the heterosexual transmission of hepatitis C
50 Citations1999G Neumayr, A Propst +3 more
The risk of HCV transmission between monogamous sex partners does not depend on the duration of sexual exposure and spouses of patients with HCV viraemia and chronic liver disease have a low risk for acquiring HCV.
TransfusionSexual transmission of hepatitis C virus to a repeat blood donor
40 Citations1997Carmen Capelli, Daniele Prati +7 more
Heterosexual transmission of HCV can occur in the absence of a long‐lasting contact, and the infection can be asymptomatic, so it remains to be determined whether the sexual partners ofHCV‐infected subjects should be deferred from blood donation.
Sexually Transmitted DiseasesIncidence and Determinants of Hepatitis C Virus Infection Among Individuals at Risk of Sexually Transmitted Diseases Attending a Human Immunodeficiency Virus Type 1 Testing Program
38 Citations1997Massimo Giuliani, F. Caprilli +8 more
Evaluating the incidence of HCV infection in a population at risk for human immunodeficiency virus type 1 (HIV‐1) infection and other sexually transmitted diseases (STD) and identifying factors associated with HCV seroconversion suggests a role of sexual practices in the transmission of the infection.
European Journal of EpidemiologySexual and non-sexual intrafamilial spread of hepatitis C virus: Intrafamilial transmission of HCV
35 Citations1998Neşe Saltoğlu, Yeşim Taşova +2 more
It is concluded that the intrafamilial transmission of HCV is possible but occurs at a low rate and the prevalence of anti-HCV in the families of index patients was significantly higher than in the controls.
European Journal of EpidemiologyHepatitis C virus infection in family setting
31 Citations1998Vincenzo Guadagnino, Tommaso Stroffolini +6 more
It is found that sexual contact and any parenteral exposure both play an independent role in the spread of HCV infection in the family setting and in univariate analysis HCV seropositivity was associated with surgical intervention, use of glass syringes and hospitalization.
InfectionHepatitis C virus infection in households of anti-HCV chronic carriers in Italy: A multicentre case-control study
28 Citations1997Evangelista Sagnelli, Giovanni Battista Gaeta +6 more
Findings are not in compliance with the statement that household contacts of HCV carriers are at increased risk ofHCV infection, but may suggest that the true anti-HCV prevalence in the general population in Italy is nearly 2.5 times as high as the 1.3% found in Italian blood donors.