Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
JAMAPublished 22 October 1997
Lindsay A. Farrer
Citations4,516
SJR quartileQ1
SJR score5.35
SNIP10.71
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TL;DR
The APOE∈4 allele represents a major risk factor for AD in all ethnic groups studied, across all ages between 40 and 90 years, and in both men and women.
Abstract
The APOE epsilon4 allele represents a major risk factor for AD in all ethnic groups studied, across all ages between 40 and 90 years, and in both men and women. The association between APOE epsilon4 and AD in African Americans requires clarification, and the attenuated effect of APOE epsilon4 in Hispanics should be investigated further.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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