Efficacy of Nocturnal Nasal Ventilation in Stable, Severe Chronic Obstructive Pulmonary Disease During a 3-Month Controlled Trial
Mayo Clinic ProceedingsPublished 1 June 1996
Peter C. Gay, Rolf D. Hubmayr, Randolph W. Stroetz
Citations168
SJR quartileQ1
SJR score2.00
SNIP2.28
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Disabled but clinically stable patients with COPD and hypercapnia do not readily accept and are unlikely to benefit from nocturnal nasal ventilation, and Sham treatment did not lower PaCO2.
Abstract
Disabled but clinically stable patients with COPD and hypercapnia do not readily accept and are unlikely to benefit from NNV.
Keywords
Medicine
Elsevier eBooksPrinciples and Practice of Sleep Medicine
5,133 Citations2011Meir H. Kryger, Thomas Roth +1 more
BMJTwo-, six-, and 12-minute walking tests in respiratory disease.
1,656 Citations1982R. J. A. Butland, J. A. Pang +3 more
Over the ensuing seven months she had three more clinical relapses, each accompanied by reappearance in the stools of either the organism or its cytotoxin, or both, and maintenance treatment with oral vancomycin 125 mg eight-hourly was begun.
SLEEPGuidelines for the Multiple Sleep Latency Test (MSLT): A Standard Measure of Sleepiness
1,588 Citations1986Mary A. Carskadon
The multiple sleep latency test (MSLT) is used in the assessment and diagnosis of disorders of excessive somnolence and to evaluate daytime sleepiness in relation to various therapeutic or experimental manipulations, such as administering drugs and altering the length or timing of nocturnal sleep.
New England Journal of MedicineReversal of Acute Exacerbations of Chronic Obstructive Lung Disease by Inspiratory Assistance with a Face Mask
716 Citations1990Laurent Brochard, Daniel Isabey +8 more
Inspiratory positive airway pressure delivered by a face mask can obviate the need for conventional mechanical ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease.
SLEEPThe Sleep Disorders Questionnaire I: Creation and Multivariate Structure of SDQ
554 Citations1994Alan B. Douglass, Robert A. Bornstein +6 more
The development of the Sleep Disorders Questionnaire (SDQ) from the Sleep Questionnaire and Assessment of Wakefulness of Stanford University is described in detail and the extraction of the best question items from the SQAW and their subsequent rewording in the SDQ are described.
American Journal of Respiratory and Critical Care MedicineNasal Pressure Support Ventilation Plus Oxygen Compared With Oxygen Therapy Alone in Hypercapnic COPD
479 Citations1995Daniel Jones, E Paul +2 more
Nasal positive-pressure ventilation may be a useful addition to LTOT in stable hypercapnic COPD as compared with run-in and oxygen alone, and quality of life with oxygen plus NPSV was significantly better than with oxygen alone.
Mayo Clinic ProceedingsPrinciples and Practice of Sleep Medicine
343 Citations1990Philip R. Westbrook
Journal of Neurology Neurosurgery & PsychiatrySleep Disorders. Diagnosis and Treatment
309 Citations1979JOHN EVANS
American Review of Respiratory DiseaseNocturnal Positive-Pressure Ventilation via Nasal Mask in Patients with Severe Chronic Obstructive Pulmonary Disease
272 Citations1991David A. Strumpf, Richard P. Millman +5 more
It is indicated that nocturnal nasal ventilation is not well tolerated by and brings about minimal improvements in stable outpatients with severe COPD.
CHEST JournalPredictive Factors of Long-term Compliance With Nasal Continuous Positive Airway Pressure Treatment in Sleep Apnea Syndrome
242 Citations1994J.-C. Meurice, P. Doré +5 more
The long-term acceptability of treatment with nasal continuous positive airway pressure (CPAP) was studied prospectively in 44 patients with obstructive sleep apnea syndrome and confirmed the importance of supervision of the time counter, as well as regular encouragement of patients to use the treatment as long as possible each night, to extract a maximum benefit from treatment by nasal CPAP.
PubMedNocturnal positive pressure ventilation via nasal mask.
185 Citations1987Gerald R. Kerby, Linda S. Mayer +1 more
Five patients with chronic respiratory failure from neuromuscular disease and symptomatic worsening nocturnal hypoventilation were treated withNocturnal ventilatory support, and symptoms of headache, insomnia/somnolence, and impaired intellectual capacity rapidly disappeared.
American Review of Respiratory DiseaseEfficacy of Nocturnal Nasal Ventilation in Patients with Restrictive Thoracic Disease
179 Citations1992Nicholas S. Hill, Scott E. Eveloff +2 more
It is concluded that NNV administered by the BIPAP ventilator is effective in ameliorating nocturnal hypoventilation and daytime symptoms in patients with chronic CO2 retention caused by severe restrictive thoracic diseases.
Archives of Pediatrics and Adolescent MedicineSleep Disorders: Diagnosis and Treatment
162 Citations1999
ThoraxDomiciliary nocturnal nasal intermittent positive pressure ventilation in hypercapnic respiratory failure due to chronic obstructive lung disease: effects on sleep and quality of life.
152 Citations1992Mark Elliott, Anita K. Simonds +3 more
Nasal intermittent positive pressure ventilation can be used effectively at home during sleep in selected patients with chronic obstructive lung disease and its future place in management can be established only by formal comparison with long term oxygen therapy.
The American Journal of MedicineSustained reversal of chronic hypercapnia in patients with alveolar hypoventilation syndromes
141 Citations1981Stuart M. Garay, Gerard M. Turino +1 more
This study represents the first published long-term follow-up regarding this mode of treatment in patients with alveolar hypoventilation using "noninvasive" nocturnal mechanical ventilation at home.
PubMedA sleep-induced apneic threshold and its consequences.
139 Citations1986Jerome A. Dempsey, James B. Skatrud
It is shown that fluctuating chemical stimuli and the accompanying instability in ventilatory control during sleep can cause obstructive apnea, at least under conditions where chemoreceptor stimuli are sufficient to initiate some inspiratory effort but insufficient to insure a completely patent upper airway.
The LancetEffect of negative pressure ventilation in severe chronic obstructive pulmonary disease
135 Citations1992Stanley H. Shapiro
NPV as used in this study is difficult to apply and ineffective when used with the aim of resting the respiratory muscles in patients with stable COPD.
American Review of Respiratory DiseaseNocturnal Positive Pressure Ventilation Via A Nasal Mask
109 Citations1987Colin E. Sullivan, Elizabeth R. Ellis
PubMedMean and instantaneous expiratory flows, FVC and FEV1: prediction equations from a probability sample of Michigan, a large industrial state.
109 Citations1987A Miller, J C Thornton +4 more
These regression equations provided similar predicted values for FVC and FEV1 in nonsmokers to other models in wide use to help understand mean and instantaneous flows in normal men, but not in normal women.
CHEST JournalEffect of Daily Intermittent Rest of Respiratory Muscles in Patients with Severe Chronic Airflow Limitation (CAL)
100 Citations1984Norma M.T. Braun, William D. Marino
European Respiratory JournalLong-term nasal ventilation in neuromuscular disorders: report of a consensus conference
98 Citations1993Dominique Robert, Willig Tn +2 more
This report summarizes recommendations issuing from a group of authorities on neuromuscular disorders met to establish a consensus concerning the application of nasal Ventilation, in the clinical setting, for patients with Duchenne's muscular dystrophy, non-Duchenne myopathies and the spinal muscular atrophies.
CHEST JournalEfficacy of Positive vs Negative Pressure Ventilation in Unloading the Respiratory Muscles
80 Citations1990Michael J. Belman, Guy W. Soo Hoo +2 more
It is concluded that in the short term, PPV is more effective than NPV in reducing diaphragmatic activity and may be the preferred method of assisted ventilation in future studies of ventilatory muscle rest therapy.
European Respiratory JournalComparison of nasal pressure support ventilation with nasal intermittent positive pressure ventilation in patients with nocturnal hypoventilation
76 Citations1993LJ Restrick, Nick C. Fox +4 more
NPSV was as effective as NIPPV in patients with nocturnal hypoventilation, which suggests that these patients are able to trigger the ventilator adequately, and the lower cost of NPSV will make it accessible to more patients with chronic lung disease.
Mayo Clinic ProceedingsNocturnal Nasal Ventilation for Treatment of Patients With Hypercapnic Respiratory Failure
70 Citations1991Peter C. Gay, Ashokakumar M. Patel +2 more
It is concluded that nocturnal nasal ventilation is well tolerated by most patients and may improve alveolar ventilation and arterial oxygenation in patients with chronic respiratory failure.
Respiration PhysiologyEffects of inspiratory support upon breathing in humans during wakefulness and sleep
62 Citations1993Martha J. Morrell, Steven A. Shea +2 more
During non-REM sleep, inspiratory mechanical support is associated with a compensatory decrease in efferent inspiratory activity to achieve a similar tidal volume with maintenance of arterial PCO2.
American Review of Respiratory DiseaseNasal Continuous Positive Airway Pressure Facilitates Respiratory Muscle Function during Sleep in Severe Chronic Obstructive Pulmonary Disease
46 Citations1991Basil J. Petrof, R. John Kimoff +3 more
Results indicate that nasal CPAP can effectively reduce inspiratory muscle effort during sleep in patients with severe COPD.
CHEST JournalVariability of Arterial Blood Gas Values Over Time in Stable Medical ICU Patients
43 Citations1994Scott A. Sasse, Priscilla A. Chen +1 more
The spontaneous variability of arterial blood gas and pH values (ABGs) was examined in a group of 28 typical stable medical ICU patients under a variety of ventilatory conditions and it is concluded that this variability should be taken into account when making clinical decisions based on ABG values.
ThoraxNasal masks for domiciliary positive pressure ventilation: patient usage and complications.
40 Citations1994D J Meecham Jones, G M Braid +1 more
Although complications resulting from nasal mask usage are common, early identification of patients at risk of developing such complications and appropriate intervention will result in improved patient compliance.
ThoraxInduction of sleep apnoea with negative pressure ventilation in patients with chronic obstructive lung disease.
33 Citations1992Robert D. Levy, M G Cosio +3 more
Positive pressure ventilation applied during sleep to patients with advanced chronic obstructive lung disease may result in the development of recurrent episodes of apnoea and hypopnoeA as well as altered sleep quality, which could limit its clinical applicability.
PubMedHome positive pressure ventilation via nasal mask for patients with neuromusculoskeletal disorders.
29 Citations1989P Léger, J Jennequin +3 more
The majority of the symptoms of hypoventilation rapidly disappeared with nocturnal ventilation and the daytime PaO2 and PaCO2 improved significantly allowing the patients to perform more daily activities.
AnaesthesiaInspiratory muscle effort during nasal intermittent positive pressure ventilation in patients with chronic obstructive airways disease
29 Citations1993M W Elliott, David A. Mulvey +3 more
Effective intermittent positive pressure ventilation can be achieved noninvasively using a nasal mask, but patient comfort may be compromised and respiratory effort increased unless the trigger threshold is low and the response time of the ventilator short.
CHEST JournalClinical Intervention in Chronic Respiratory Failure
17 Citations1990James G. Martin
A number of investigators have confirmed that inspiratory muscle training (IMT) can improve inspiratory Muscle performance in patients with COPD, which in some cases is also accompanied by improvement in exercise performance...