Cortical lesions and brain atrophy in MS
Journal of the Neurological SciencesPublished 1 June 2005
Alexandra Kutzelnigg, Hans Lassmann
Citations133
SJR quartileQ1
SJR score1.15
SNIP0.99
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TL;DR
The possibility that disease involvement of grey matter structures may significantly contribute to clinical disability in multiple sclerosis patients is discussed.
Abstract
Multiple sclerosis is generally considered a disease of the white matter. However, this is only one pathological aspect of the disease as demyelination is prominent in the grey matter of deep cerebral nuclei and the cerebral cortex. In this review, we discuss the possibility that disease involvement of grey matter structures may significantly contribute to clinical disability in multiple sclerosis patients.
Keywords
MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology
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