Some observations on axonal degeneration resulting from superficial lesions of the cerebral cortex
The Journal of Comparative NeurologyPublished 1 August 1973
Haring J. W. Nauta, Albert B. Butler, John A. Jane
Citations56
SJR quartileQ2
SJR score1.08
SNIP0.80
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TL;DR
Thermal lesions were placed in the superficial cell layers of the neocortex in rats, cats, and tree shrews, and the resulting intracortical axonal degeneration was studied by the Fink‐Heimer technique and by electron microscopy.
Abstract
Abstract Thermal lesions were placed in the superficial cell layers of the neocortex in rats, cats, and tree shrews, and the resulting intracortical axonal degeneration was studied by the Fink‐Heimer technique and by electron microscopy. Certain features of the degeneration resulting from such lesions are common to each cortical area studied. Despite the finding of appreciable axonal degeneration spreading tangentially, the most conspicuous axonal degeneration in each area studied was noted to be oriented vertically with terminations occurring in the deeper layers, especially in the region of the large pyramidal cells of layer V. The bulk of the degeneration in the deeper layers was confined to an area coextensive with the boundaries of the superficial lesion.
Keywords
MedicineNeuroscience
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