Dinucleotide repeat polymorphism at the human interleukin 9 gene
Nucleic Acids ResearchPublished 1 January 1991Open access
Mihael H. Polymeropoulos, H. Xiao, D.S. Rath, Carl R. Merril
Citations14
SJR quartileQ1
SJR score7.78
SNIP4.71
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Abstract
M.H. Polymeropoulos, H. Xiao, D.S. Rath, C.R. Merril; Dinucleotide repeat polymorphism at the human interleukin 9 gene, Nucleic Acids Research, Volume 19,
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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Analysis of P40 genomic clones reported here shows that the human and mouse P40 genes consist of 5 exons spread over approximately 4 kb of DNA and organized in a similar fashion in both species, suggesting that the gene is not easily activated in B lymphocytes and in monocytes.
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Mouse and human cDNA clones encoding the T-cell and mast cell growth factor P40, now designated IL-9, were used to identify DNA restriction fragment length polymorphisms (RFLPs) in sets of somatic cell hybrids and between inbred strains of mice and interspecific backcross progeny.
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