Conflicts of Interest at Medical Journals: The Influence of Industry-Supported Randomised Trials on Journal Impact Factors and Revenue – Cohort Study
PLoS MedicinePublished 26 October 2010Open access
Andreas Lundh, Marija Barbateskovic, Asbjørn Hróbjartsson, Peter C Gøtzsche
Citations123
SJR quartileQ1
SJR score4.28
SNIP3.21
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
The effect of publication of large industry-supported trials on citations and journal income, through reprint sales, in six general medical journals is investigated.
Abstract
publication of industry-supported trials was associated with an increase in journal impact factors. Sales of reprints may provide a substantial income. We suggest that journals disclose financial information in the same way that they require them from their authors, so that readers can assess the potential effect of different types of papers on journals' revenue and impact.
Keywords
Social SciencesDecision SciencesPharmacology, Toxicology and Pharmaceutics
BMJPharmaceutical industry sponsorship and research outcome and quality: systematic review
2,163 Citations2003Joel Lexchin, Lisa A Bero +2 more
Investigating whether funding of drug studies by the pharmaceutical industry is associated with outcomes that are favourable to the funder and whether the methods of trials funded by pharmaceutical companies differ from the methods in trials with other sources of support found systematic bias favours products which are made by the company funding the research.
JAMAReporting and Interpretation of Randomized Controlled Trials With Statistically Nonsignificant Results for Primary Outcomes
776 Citations2010Isabelle Boutron
The reporting and interpretation of findings was frequently inconsistent with the results and the nature and frequency of distorted presentation or "spin" was identified in published reports of randomized controlled trials with statistically nonsignificant results for primary outcomes.
JAMAPrevalence of Articles With Honorary Authors and Ghost Authors in Peer-Reviewed Medical Journals
550 Citations1998Annette Flanagin
A substantial proportion of articles in peer-reviewed medical journals demonstrate evidence of honorary authors or ghost authors.
PLoS MedicineMedical Journals Are an Extension of the Marketing Arm of Pharmaceutical Companies
501 Citations2005Richard Smith
PubMedGuest authorship and ghostwriting in publications related to rofecoxib: a case study of industry documents from rofecoxib litigation.
451 Citations2008Joseph S. Ross, Kevin P. Hill +2 more
This case-study review of industry documents demonstrates that clinical trial manuscripts related to rofecoxib were authored by sponsor employees but often attributed first authorship to academically affiliated investigators who did not always disclose industry financial support.
New England Journal of MedicineImportance of the Lay Press in the Transmission of Medical Knowledge to the Scientific Community
404 Citations1991David P. Phillips, Evan Kanter +2 more
Columns in the Times that were covered by the Times received a disproportionate number of scientific citations in each of the 10 years after the Journal articles appeared, and the effect was strongest in the first year after publication.
Annals of Internal MedicineNarrative Review: The Promotion of Gabapentin: An Analysis of Internal Industry Documents
333 Citations2006Michael A. Steinman, Lisa Bero +2 more
How marketing strategies and tactics for gabapentin were developed and used in the mid- and late 1990s are described, focusing on how certain groups of physicians were targeted as recipients of and vehicles for promotion.
Annals of Internal MedicinePharmaceutical Advertisements in Leading Medical Journals: Experts' Assessments
256 Citations1992Michael S. Wilkes, Bruce Doblin +1 more
Many advertisements contained deficiencies in areas in which the FDA has established explicit standards of quality, including information on efficacy, which was judged by two or more reviewers to have little or no educational value.
The British Journal of PsychiatryInterface between authorship, industry and science in the domain of therapeutics
218 Citations2003David Healy, Dinah Cattell
The emerging style of authorship in industry-linked articles can deliver good-quality articles, but it raises concerns for the scientific base of therapeutics, and the literature profiles and citation rates of industry- linked and non-industry- linked articles differ.
PLoS ONECharacteristics Associated with Citation Rate of the Medical Literature
163 Citations2007Abhaya V. Kulkarni, Jason W. Busse +1 more
Large trials, with group authorship, industry-funded, with industry-favoring results, in oncology or cardiology were associated with greater subsequent citations.
JAMAThe Journal Impact Factor Denominator
126 Citations2009Marie McVeigh, Stephen J. Mann
This journal-specific analysis identifies the journal sections, subsections, or both that contain materials likely to be considered scholarly works, and which therefore have the potential to be cited.
International Journal of EpidemiologyCommentary: The power of the unrelenting impact factor—Is it a force for good or harm?
123 Citations2006Richard Smith
The impact factor that was born in this article has done little to reduce the citation of fraudulent data and may well have encouraged such citations.
BMJCommercial influence and the content of medical journals
99 Citations2006Joel Lexchin, Donald W. Light
PLoS MedicineGhostwriting: The Dirty Little Secret of Medical Publishing That Just Got Bigger
62 Citations2009The PLoS Medicine Editors
In this case, the interest was not in the specific drugs, but in the issue of ghostwriting itself, a topic the lawyers representing injured women in the litigation have long been interested in and published on replacement therapy.
PubMedPharmaceutical advertising revenue and physician organizations: how much is too much?
40 Citations1999Peter Glassman, J Hunter-Hayes +1 more
Potential financial conflicts of interest arising from pharmaceutical advertisements in medical journals may be substantial and the impact on professional societies' financial independence and behavior is unknown.
Journal of the Royal Society of MedicineLapses at the New England Journal of Medicine
38 Citations2006Richard Smith
CirculationDifferential Citation Rates of Major Cardiovascular Clinical Trials According to Source of Funding
31 Citations2008David Conen, José Pinheiro Torres +1 more
Consideration should be given to more extensive promotion of clinical trial results that are funded by not-for-profit organizations, as the number of citations per publication per year appears to be biased in favor of for-profit entities.
International Journal of Technology Assessment in Health CareHOW IMPORTANT IS THE SIZE OF A REPRINT ORDER?
9 Citations2003Sally Hopewell, Mike Clarke
Assessment of the impact of articles with very high reprint orders by measuring their citation in the subsequent literature as compared with a control group of articles found that articles with a high-reprint order were cited more frequently than other articles.
