Coffee and cardiovascular risk; an epidemiological study

The hypothesis that coffee use does not affect the risk of cardiovascular disease is supported by a review of the published results of 17 cohort studies and 10 casecontrol studies.

Abstract

textabstractThis thesis comprises several studies on the effect of coffee and caffeine on
\ncardiovascular risk in general, and the effect on serum lipids, blood pressure and
\nselected hemostatic variables in particular.
\nThe association between coffee use and cardiovascular morbidity and mortality
\nwas evaluated by a review of the published results of 17 cohort studies and 10 casecontrol
\nstudies. In the interpretation of the results of these studies, it is important to
\ntake into account the strong relationship of coffee consumption and other habits
\nassociated with cardiovascular disease, such as smoking and a high dietary fat intake.
\nWhen these confounders are not considered in the analysis, the risk of coffee use for
\ncardiovascular disease may be overestimated. Most case-control studies yielded positive
\nresults, i.e. coffee use was observed to increase the risk of a cardiovascular event. Casecontrol
\nstudies, however, are subject to several forms of bias which could lead to
\noverestimation of the coffee-cardiovascular disease association. The majority of cohort
\nstudies, which are more reliable, support the hypothesis that coffee use does not affect
\nthe risk of cardiovascular disease