The effect of <scp>l</scp>-ascorbate on catecholamine biosynthesis (<i>Short Communication</i>)
Biochemical JournalPublished 1 March 1973Open access
K. J. Stone, B. H. Townsley
Citations32
SJR quartileQ1
SJR score2.06
SNIP0.98
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TL;DR
L-Ascorbate stimulates the enzymic hydroxylation of phenylalanine in vitro by recycling tetrahydrobiopterin, which reduces O(2) utilized in the reaction.
Abstract
l-Ascorbate stimulates the enzymic hydroxylation of phenylalanine in vitro by recycling tetrahydrobiopterin, which reduces O(2) utilized in the reaction. It is suggested that ascorbate might have a similar function in vivo; this would explain the apparent regulation of tyrosine hydroxylase and tryptophan hydroxylase activities by this vitamin.
Keywords
Agricultural and Biological SciencesMedicine
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