Statistical Estimate of the Total Number of Operons Specific for <i>Bacillus subtilis</i> Sporulation
Journal of BacteriologyPublished 1 September 1974Open access
Daslav Hranueli, P. J. Piggot, J. Mandelstam
Citations91
SJR quartileQ2
SJR score1.09
SNIP0.85
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TL;DR
As an alternative to exhaustive mapping, an attempt has been made to obtain a rough estimate of the total number of sporulation operons by statistical treatment.
Abstract
As an alternative to exhaustive mapping, an attempt has been made to obtain a rough estimate of the total number of sporulation operons by statistical treatment. Sixteen sporulation mutants taken at random were characterized biochemically and morphologically. The mutations they contained were mapped to determine whether they fell into any one of 23 known operons. From the proportion that do so (10/16), it is calculated that the most probable number of sporulation operons is 37 (68% confidence limits of 31 and 46). If allowance is made for the fact that two of the operons apparently contain mutagenic "hot spots" and the calculation is amended accordingly, the most probable numbers of operons becomes 42 (limits 33 and 59).
Keywords
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