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Visual Pathway Mediating Pineal Response to Environmental Light

SciencePublished 13 January 1967
Robert Y. Moore, Alfred Heller, Richard J. Wurtman, Julius Axelrod
Citations135
SJR quartileQ1
SJR score10.42
SNIP6.62

TL;DR

Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light.

Abstract

Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light. Response to environmental light is initiated in the retina and transmitted to the pineal by way of the central nervous system and the cervical sympathetics. The central visual pathway essential for mediation of this response is the inferior accessory optic tract. Visual pathways to thalamus and tectum do not participate in this response.

Keywords

Neuroscience