Determination of Nicotine and its Metabolite, Cotinine, in Urine by Gas Chromatography
NaturePublished 1 September 1966
A H Beckett, E. J. Triggs
Citations83
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
A VARIETY of methods have been described for the identification and determination of nicotine in biological fluids however, they lack sensitivity, specificity and are tedious for routine analysis.
Abstract
A VARIETY of methods have been described for the identification and determination of nicotine in biological fluids1–4; however, they lack sensitivity, specificity and are tedious for routine analysis.
Keywords
ChemistryMedicineBiochemistry, Genetics and Molecular Biology
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The quantitation of nicotine and its metabolites in the body fluids of smokers would be helpful for the investigation of the relation between nicotine exposure and heart disease and should also give a more reliable estimate of the quantities of other tobacco smoke ingredients to which the body is exposed.
