Mild Cognitive Impairment and Everyday Function: Evidence of Reduced Speed in Performing Instrumental Activities of Daily Living
American Journal of Geriatric PsychiatryPublished 1 May 2008
Virginia G. Wadley, Ozioma C. Okonkwo, Michael Crowe, Lesley A. Ross
Citations173
SJR quartileQ1
SJR score1.38
SNIP1.21
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
These results suggest that slower speed of task performance is an important component and perhaps an early marker of functional change in MCI that would not be detected using traditional measurements of daily function. Future research should address the question of whether performance-based functional measures, as well as simple queries regarding whether functional activities take longer than usual to complete, may improve the prediction of future cognitive decline and disease progression among those individuals in whom MCI represents impending dementia.
Keywords
Medicine
Journal of Internal MedicineMild cognitive impairment as a diagnostic entity
7,843 Citations2004Ronald C. Petersen
It is suggested that the diagnosis of mild cognitive impairment can be made in a fashion similar to the clinical diagnoses of dementia and AD, and an algorithm is presented to assist the clinician in identifying subjects and subclassifying them into the various types of MCI.
Journal of Internal MedicineMild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
4,975 Citations2004Bengt Winblad, Katie Palmer +23 more
A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics.
The LancetMild cognitive impairment
3,865 Citations2006Serge Gauthier, Barry Reisberg +17 more
Although there are no pharmacological treatments at present that are capable of delaying the long-term progression of MCI to dementia, there is some evidence of short-term symptomatic benefits with acetylcholinesterase inhibitors.
JAMAEffects of Cognitive Training Interventions With Older Adults
2,001 Citations2002Karlene Ball, Daniel B. Berch +11 more
Results support the effectiveness and durability of the cognitive training interventions in improving targeted cognitive abilities and were of a magnitude equivalent to the amount of decline expected in elderly persons without dementia over 7- to 14-year intervals.
JAMALong-term Effects of Cognitive Training on Everyday Functional Outcomes in Older Adults
1,473 Citations2006Sherry L. Willis, Sharon L. Tennstedt +10 more
Cognitive training resulted in improved cognitive abilities specific to the abilities trained that continued 5 years after the initiation of the intervention, and booster training for the speed of processing group showed a significant effect on the performance-based functional measure of everyday speed ofprocessing.
Archives of NeurologyMild Cognitive Impairment as a Clinical Entity and Treatment Target
904 Citations2005Ronald C. Petersen, John C. Morris
This work concludes that a diagnostic approach combining a careful, structured interview and the appropriate neuropsychological tests can discriminate those individuals with MCI likely to experience cognitive deterioration from those with a benign prognosis.
NeurologyMild cognitive impairment
545 Citations2006Anja Busse, Anke Hensel +3 more
It has been assumed that each MCI subtype is associated with an increased risk for a particular type of dementia, but this study finds that each subtype can only partially agree with this.
NeurologyFunctional deficits in patients with mild cognitive impairment
477 Citations2002Matthias H. Tabert, Steven M. Albert +6 more
In patients with MCI, the patient’s lack of awareness of functional deficits identified by informants strongly predicts a future diagnosis of AD, suggesting that clinicians evaluating MCI patients should obtain both self-reports and informant reports offunctional deficits to help in prediction of long-term outcome.
Archives of NeurologyPredicting Conversion to Alzheimer Disease Using Standardized Clinical Information
361 Citations2000Ella Daly, Deborah Zaitchik +4 more
Subjects who met the criteria for questionable AD had a variety of trajectories during a 3-year follow-up, suggesting that diverse factors may influence the functional changes observed in this population.
NeurologyImpaired financial abilities in mild cognitive impairment
318 Citations2003H. Randall Griffith, Katherine Belue +5 more
Patients with amnestic MCI as a group demonstrate impairments across a range of financial abilities, however, existing diagnostic criteria for MCI should be applied flexibly to include mild impairments in higher order activities of daily life such as financial capacity.
Aging & Mental HealthThe impact of speed of processing training on cognitive and everyday performance
318 Citations2005Jerri D. Edwards, Virginia G. Wadley +4 more
This study provides additional evidence that speed of processing training has the potential to enhance everyday functions that maintain independence and quality of life, particularly when the training is targeted toward individuals who most need it.
GerontologyTimed Instrumental Activities of Daily Living Tasks: Relationship to Cognitive Function and Everyday Performance Assessments in Older Adults
286 Citations2002Cynthia Owsley, Michael E. Sloane +2 more
TIADL measures may prove useful in evaluating the everyday effectiveness of cognitive interventions targeted at increasing information-processing speed, and suggest a unique role for an everyday competence test that focuses on the timely completion of everyday tasks, rather than on an assessment of accuracy alone.
Alzheimer Disease & Associated DisordersMCI is Associated With Deficits in Everyday Functioning
285 Citations2006Sarah Farias, Dan Mungas +4 more
The current findings suggest that individuals with MCI demonstrate deficits in a wide range of everyday functions but that the magnitude of these changes is greatest for those functional abilities that rely heavily on memory.
NeurologyVariations in case definition affect prevalence but not outcomes of mild cognitive impairment
261 Citations2003John D. Fisk, Heather Merry +1 more
Memory complaints and intact IADL may be unnecessary requirements for a case definition of MCI in population-based samples, but the potential for improvement of a substantial proportion of those with MCI needs to be acknowledged.
The LancetMild cognitive impairment in older people
251 Citations2002Alistair Burns, Michael Zaudig
Hippocampal volumes and N-acetyl aspartate/creatine spectroscopy were the most sensitive assessments discriminating people with mild cognitive impairment from Alzheimer's disease and Combination assessments were better at discriminating these two groups from normal controls.
NeurologyRestriction in complex activities of daily living in MCI
242 Citations2006Karine Pérès, Virginie Chrysostome +4 more
BrainCognitive process in preclinical phase of dementia
230 Citations1998Colette Fabrigoule
The results seem to show that preclinical deficits in dementia and Alzheimer's disease reflect the deterioration of a general cognitive factor, which may be interpreted as the disturbance of central, control processes.
Psychology and AgingEveryday problem solving in older adults: Observational assessment and cognitive correlates.
207 Citations1995Manfred Diehl, Sherry L. Willis +1 more
Older adults' ability to solve practical problems in 3 domains of daily living was assessed using a new measure of everyday problem solving, the Observed Tasks of Daily Living (OTDL), and found that the OTDL formed internally consistent scales representing 3 distinct factors of everyday problems.
The GerontologistEveryday Cognitive Competence in Elderly Persons: Conceptual Issues and Empirical Findings
181 Citations1996Sherry L. Willis
Seven-year longitudinal data indicate that there is relatively modest decline in performance on cognitively complex everyday tasks during the 60s, but that steeper patterns of normative decline are found in the late 70s and 80s.
The Journals of Gerontology Series BCaregivers' Judgments of the Functional Abilities of the Alzheimer's Disease Patient: A Comparison of Proxy Reports and Objective Measures
179 Citations2001David Loewenstein, Soledad Argüelles +5 more
The results indicate that caregivers were extremely accurate in predicting the functional performance of AD patients who were not impaired during objective evaluation, and caregivers significantly overestimated the ability of impaired AD patients to tell time, to identify currency, to make change for a purchase, and to utilize eating utensils.
Acta Neurologica ScandinavicaInstrumental activities of daily living: a stepping-stone towards Alzheimer's disease diagnosis in subjects with mild cognitive impairment?
178 Citations2003Louise Nygård
It is argued that the diagnosis of MCI should include rather than exclude observed or experienced changes in complex everyday life activities in order to predict or differentiate between diagnoses.
Journal of the American Geriatrics SocietyFunctional Impairment in Instrumental Activities of Daily Living: An Early Clinical Sign of Dementia?
177 Citations1999Pascale Barberger‐Gateau, Colette Fabrigoule +3 more
The predictive value of four IADLs on 3‐ and 5‐year incident dementia is estimated to be between $10,000 and $20,000 per patient, depending on the type of dementia.
Optometry and Vision ScienceTimed Instrumental Activities of Daily Living Tasks: Relationship to Visual Function in Older Adults
176 Citations2001Cynthia Owsley, Gerald McGwin +3 more
Older adults’ timed performance in everyday tasks is related to various aspects of visual function independent of the influences of other functional and health problems and advanced age, which suggests that TIADL tasks may eventually be useful as performance outcomes in intervention evaluations targeted at reversing vision impairment or minimizing its impact.
NeurocaseMild cognitive impairment and everyday functioning in older adults
145 Citations2005Holly Tuokko, Carolyn Morris +1 more
Cross-sectional and longitudinal comparisons indicated that individuals with MCI/CIND demonstrated a broad range of impairment in instrumental activities of daily living (IADL) compared to individuals with no cognitive impairment (NCI).
Journal of the American Geriatrics SocietyCognitive Correlates of Financial Abilities in Mild Cognitive Impairment
144 Citations2006Ozioma C. Okonkwo, Virginia G. Wadley +3 more
This study aims to investigate the cognitive correlates of financial abilities in mild cognitive impairment (MCI) and the effects of prior history of abuse, as well as to establish a causal relationship between abuse and depression.
International Journal of Geriatric PsychiatryDisability and mild cognitive impairment: a longitudinal population‐based study
143 Citations2001Sylvaine Artéro, Jacques Touchon +1 more
To determine whether mild cognitive deficit is associated with parallel changes in ability to perform activities of daily living, a large number of patients with mild cognitive deficits are randomly assigned to a either a “cognitive impairment” or “normal” group.
Journal of the International Neuropsychological SocietyEffect of memory impairment on training outcomes in ACTIVE
130 Citations2007Frederick W. Unverzagt, Linda Kasten +12 more
Results indicated that memory-impaired participants failed to benefit from Memory training but did show normal training gains after reasoning and speed training, and memory function appears to mediate response to structured cognitive interventions in older adults.
Journal of the American Geriatrics SocietyMild Cognitive Impairment and 10‐Year Trajectories of Disability in the Iowa Established Populations for Epidemiologic Studies of the Elderly Cohort
118 Citations2005Jama L. Purser, Gerda G. Fillenbaum +2 more
To apply diagnostic criteria for mild cognitive impairment to a geographically representative sample, to estimate the prevalence of MCI, and to estimate 10‐year trajectories of incident disability for cognitively intact participants and subgroups with MCI.
Journal of the American Geriatrics SocietySelf‐ and Informant Report of Financial Abilities in Patients with Alzheimer's Disease: Reliable and Valid?
115 Citations2003Virginia G. Wadley, Lindy E. Harrell +1 more
Evaluated reports by patients with Alzheimer's disease and their caregivers regarding the patients' premorbid and current financial abilities and the consistency, stability, and accuracy of reports are evaluated.
Journal of the American Geriatrics SocietyChanges in Everyday Function in Individuals with Psychometrically Defined Mild Cognitive Impairment in the Advanced Cognitive Training for Independent and Vital Elderly Study
114 Citations2007Virginia G. Wadley, Michael Crowe +5 more
The aim is to examine trajectories of change in everyday function for individuals with cognitive deficits suggestive of mild cognitive impairment (MCI) in the context of clinical practice.
American Journal of Geriatric PsychiatryFunctional Significance of Mild Cognitive Impairment in Elderly Patients Without a Dementia Diagnosis
109 Citations1999Steven M. Albert, Kristin S. Michaels +6 more
Correlations between self- and informant reports of functional status were significantly lower in theCDRS 0.
NeurocaseAbnormal visual search in mild cognitive impairment and Alzheimer’s disease
76 Citations2005Andrea Tales, Judy Haworth +3 more
The pattern of results displayed by the MCI group indicates that patients who appear clinically to suffer only from a deficit in memory also display a deficits in visual attention-related processing, which although not as severe as those with AD, represents a significant detriment in such performance compared to that seen in healthy ageing.
Dementia and Geriatric Cognitive DisordersCognitive Profiles in Alzheimer’s Disease and in Mild Cognitive Impairment of Different Etiologies
69 Citations2006David Loewenstein, Amarilis Acevedo +6 more
Analysis of cognitive profiles of nondemented patients with MCI diagnosed with prodromal Alzheimer’s disease and those diagnosed with vascular disease found that both groups could be distinguished from dementia patients with regards to performance on measures of memory but not on non-memory measures.
American Journal of Geriatric PsychiatryCognitive Impairment, Chronic Disease Burden, and Functional Disability: A Population Study of Older Italians
43 Citations2007James M. Scanlan, Nancy Binkin +4 more
Cognitive impairment assessed by the Mini-Cog is a more powerful predictor of impaired ADLs than disease burden in older adults and could be useful in assessing older population assistance needs.
Dementia and Geriatric Cognitive DisordersDeterioration of Controlled Processes in the Preclinical Phase of Dementia: A Confirmatory Analysis
39 Citations2000Hélène Amieva, Isabelle Rouch‐Leroyer +2 more
The results showed that the future demented subjects, although significantly impaired compared to elderly controls, were able to increase their performance across trials, lending more weight to the hypothesis of a preclinical impairment of controlled processes in dementia.
Journal of Clinical and Experimental NeuropsychologySpecific Impairments of Selective Attention in Mild Alzheimer’s Disease
37 Citations2005Riccardo Pignatti, Marco Rabuffetti +5 more
While psychomotor speed and lower attention levels (sensorimotor) are preferentially impaired in subcortical forms of dementia, the higher levels of selective and divided attention could be the first to deteriorate and appear more markedly disrupted in the Alzheimer type of dementia.
NeuropsychologiaInspection time in non-demented older adults with mild cognitive impairment
23 Citations2006Kathryn R. Bonney, Osvaldo P. Almeida +5 more
Group comparison showed that participants with MCI performed significantly worse on IT than controls and was not affected by years of education, suggesting IT may be a useful assessment tool for improving the identification of older adults at risk for clinically relevant cognitive decline.
PubMed[A detection of very mild Alzheimer's disease and MCI by memory complaints and deterioration of IADL in a questionnaire for a memory clinic].
3 Citations2006Megumi Ueda, Yutaka Takayama +2 more
Findings indicated that an exploration of memory complaints and deteriorations of IADL was useful for the detection of MCI and very mild AD, especially 7 items described above could be used as a simple questionnaire for the elderly.
