Sunlight: A major factor associated with the development of melanocytic nevi in Australian schoolchildren
Journal of the American Academy of DermatologyPublished 1 January 1994
John W. Kelly, Jason K. Rivers, Robert MacLennan, Simone L. Harrison, A. Lewis, Bruce Tate
Citations222
SJR quartileQ1
SJR score1.31
SNIP1.44
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TL;DR
Latitude of residence, and by implication ambient UV radiation, is strongly related to nevus prevalence in young Australian children, however, these differences diminish with age and may disappear by 15 years of age.
Abstract
Latitude of residence, and by implication ambient UV radiation, is strongly related to nevus prevalence in young Australian children. However, these differences diminish with age and may disappear by 15 years of age.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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Determination of risk factors allows the identification of that subset of the population most at risk for the development of cutaneous malignant melanoma, and can help to focus preventive measures on the more susceptible subgroups of the Population.
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CancerDevelopment and elimination of pigmented moles, and the anatomical distribution of primary malignant melanoma
149 Citations1973E.M. Nicholls
In Sydney, Australia, the number of pigmented moles per person increases to age 15 in males and 20‐29 in females, the most exposed parts of the body reaching peak values soonest, and a decline then begins so that moles are almost absent in persons 80 years old.
Recent results in cancer research/Recent Results in Cancer ResearchEpidemiology of Malignant Melanoma: Pigmentary Traits, Ultraviolet Radiation, and the Identification of High-Risk Populations
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A case-control study begun in 1979 to identify factors responsible for the observed high incidence of malignant melanoma among Caucasians was reported on, with results for a subset of the available risk factor data, including pigmentary traits, sun exposure, and family history variables.
British Journal of CancerMalignant melanoma in relation to moles, pigmentation, and exposure to fluorescent and other lighting sources
148 Citations1986Mark Elwood, Catherine Williamson +1 more
Significantly increased risks of melanoma were found in subjects with 3 or more raised moles on the upper arms, in association with heavy freckling of the face and arms, and with a tendency to sunburn easily and tan poorly, these factors having independent effects.
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Findings in children are similar to those seen in studies of malignant melanoma among adults and suggest that strategies to reduce melanoma incidence should begin with young children.
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Dysplastic nevi are supported as markers of increased risk for nonfamilial melanoma in newly diagnosed incident melanoma cases with negative family histories for familial melanoma.
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Journal of the American Academy of DermatologyMelanocytic nevi in schoolchildren in Queensland
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JNCI Journal of the National Cancer InstituteEtiology of Common Acquired Melanocytic Nevi: Constitutional Variables, Sun Exposure, and Diet<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>
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The prevalence of nevi was higher in women than men, fell with age up to about 35 years of age, and was low in those born outside Australia, while the protective effect of birthplace outside Australia appeared to be due to the corresponding low mean annual hours of bright sunlight at places of residence when 10-24 years ofAge.
Archives of DermatologyBenign Pigmented Nevi in Children
60 Citations1992Deborah J. Pope
The hypothesis that environmental factors influence the prevalence of moles in childhood is supported, as a propensity to burn rather than tan, a history of sunburn, a tendency to freckle, and a life-style involving increased sun exposure were associated with an increased prevalence of mole prevalence.
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59 Citations2009Christian Sigg, F. Pelloni
In 939 schoolchildren aged 8-16 years skin complexion was determined by a system of seven categories: in fair skin type nevi are most frequent, decreasing in number by increasing of pigment content and in freckles have higher mean nevus count in every category of skin complexion.
The Journal of Dermatologic Surgery and OncologyPrevalence of Nevocytic Nevi on Lateral and Medial Aspects of Arms
52 Citations1978Alfred W. Kopf, M. D. Lazar +3 more
One explanation for the greater prevalence of nevi on the lateral over that on the medial aspects of the arms is that sunlight plays a role in the induction of acquired nevocytic nevi.
BMJRelation between phenotype and banal melanocytic naevi.
45 Citations1987J S English, Anthony J. Swerdlow +5 more
This is the first study to find any relation between melanocytic naevi and phenotypic factors in a white population and no significant associations were shown for parity or use of oral contraceptives or other steroid hormones.
Australasian Journal of DermatologyTHE AUSTRALIAN CLIMATOLOGY OF BIOLOGICALLY EFFECTIVE ULTRAVIOLET RADIATION
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A simple atmospheric model is used to calculate the dose of biologically effective ultraviolet solar radiation reaching the earth's surface and the results are presented as seasonal maps of the radiation distribution over Australia.
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39 Citations1988F.H.J. Rampen, B.A.M. Fleuren +2 more
Archives of DermatologyRelationship of Lumbosacral Nevocytic Nevi to Sun Exposure in Dysplastic Nevus Syndrome
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In 104 consecutive Caucasian patients who had histologically proved dysplastic nevi, the number and diameter of nevocytic nevi were determined in two equally sized contiguous rectangles in the lumbosacral region, consistent with the hypothesis that sunlight promotes development of more and larger nevi in individuals afflicted with dysplastics nevus syndrome.
Journal of the American Academy of DermatologyBenign pigmented nevi in children from Kidderminster, England: Prevalence and associated factors
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Data from this study supports the hypotheses that (1) the number of nevi is a risk factor for melanoma and (2) groups at high risk of melanoma may be formed in childhood.
Acta Dermato VenereologicaMelanocytic naevi in sun-exposed and protected skin in melanoma patients and controls.
27 Citations1991A Augustsson, Ulrika Stierner +2 more
The idea that sunlight plays an important role in naevi development and may explain why a high naevus count is a risk marker for malignant melanoma is supported.
British Journal of DermatologyMelanocytic naevi: clinical features and correlation with the phenotype in healthy young males in Italy
17 Citations1991Laura Brogelli, Vincenzo De Giorgi +2 more
Those subjects with blond or red hair, fair skin, blue or green eyes and with a skin type of I and II had higher numbers of naevi which were more often atypical than those subjects with dark hair, brown eyes and who were skin types III—V.
