Epilepsy and sudden death

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Abstract

In 1995, 771 epilepsy-related deaths were recorded in the United Kingdom—more than twice the number of sudden infant deaths and about half that of asthma-related deaths. 1 Office of National Statistics Monitor. DH2 96/2. 20 June, 1996; : 6-9 Google Scholar Yet, it is only recently that mortality from epilepsy, as opposed to that from any underlying disease, has again been acknowledged. 2 Epilepsy and sudden death: neurological disease and therapy. vol 7. Dekker, New York1990 Google Scholar Whilst seizure-related accidental deaths are recognised, it is less commonly appreciated that about 1:1000 people with epilepsy, usually young and in otherwise good health, die suddenly and unexpectedly each year. 3 Tennis P Cole TB Annegers JF Leestma JE McNutt M Rajput A Cohort study of incidence of sudden unexplained death in persons with seizure disorder treated with antiepileptic drugs in Saskatchewan, Canada. Epilepsia. 1995; 36: 29-36 Crossref PubMed Scopus (176) Google Scholar In such cases, necropsy commonly shows pulmonary oedema or other organ congestion but does not reveal a cause for death.