Footshock stress facilitates self-stimulation of the medial prefrontal cortex but not the lateral hypothalamus in the rat
Brain ResearchPublished 1 June 1989
Iain S. McGregor, Bernard W. Balleine, Dale M. Atrens
Citations11
SJR quartileQ2
SJR score0.85
SNIP0.72
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TL;DR
The effects of stress on self- Stimulation were investigated by exposing rats to either controllable, uncontrollable or no footshock, and self-stimulation of the lateral hypothalamus was unaffected by either footshock treatment.
Abstract
The effects of stress on self-stimulation were investigated by exposing rats to either controllable, uncontrollable or no footshock. Both controllable and uncontrollable footshock increased medial prefrontal cortex self-stimulation rates immediately as well as 24 h following treatment. Controllable footshock produced a greater enhancement than uncontrollable footshock. In contrast, self-stimulation of the lateral hypothalamus was unaffected by either footshock treatment. These results are interpreted with reference to the neurochemical response of the mesocortical dopaminergic system to acute stress.
Keywords
PsychologyNeuroscience
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