Protein Kinase C Inhibition in the Treatment of Mania
Archives of General PsychiatryPublished 1 March 2008Open access
Ayşegül Yıldız, Sebnem Guleryuz, Donna P. Ankerst, Döst Öngür, Perry F. Renshaw
Citations210
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TL;DR
Tamoxifen demonstrated antimanic properties and was remarkably well tolerated, and the findings encourage further clarification of the role of PKC in the pathophysiologic mechanism of bipolar I disorder and development of novel anti-PKC agents as potentialantimanic or mood-stabilizing agents.
Abstract
clinicaltrials.gov Identifier: NCT00411203 and isrctn.org Identifier: ISRCTN97160532.
Keywords
Medicine
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