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Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

DiabetologiaPublished 1 August 2002Open access
T. Vilsb x F ll, Thure Krarup, Sten Madsbad, Jens J. Holst
Citations514
SJR quartileQ1
SJR score3.62
SNIP2.67
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TL;DR

Lack of GIP amplification of the late phase insulin response to glucose, which contrasts markedly to the normalising effect of GLP-1, could be a key defect in insulin secretion in Type II diabetic patients.

Abstract

Lack of GIP amplification of the late phase insulin response to glucose, which contrasts markedly to the normalising effect of GLP-1, could be a key defect in insulin secretion in Type II diabetic patients.

Keywords

Medicine