Risk of morbidity from renovascular disease in elderly patients with congestive cardiac failure
The LancetPublished 1 July 1998
P. MacDowall, P A Kalra, D J O'Donoghue, S. Waldek, H. Mamtora, Kathryn M. Brown
Citations176
SJR quartileQ1
SJR score12.11
SNIP22.72
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TL;DR
Some elderly patients with occult renovascular disease on ACE inhibitors will be at risk of developing uraemia and Renal function should be closely monitored to detect any deterioration early.
Abstract
Some elderly patients with occult renovascular disease on ACE inhibitors will be at risk of developing uraemia. Renal function should be closely monitored to detect any deterioration early.
Keywords
Medicine
New England Journal of MedicineEffect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure
8,006 Citations1991The SOLVD Investigators*
The addition of enalapril to conventional therapy significantly reduced mortality and hospitalizations for heart failure in patients with chronic congestive heart failure and reduced ejection fractions.
The LancetRandomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)
1,660 Citations1997Bertram Pitt, Robert Segal +8 more
Treatment with losartan was associated with an unexpected lower mortality than that found with captopril in older heart-failure patients and there was no difference in renal dysfunction.
New England Journal of MedicineCaptopril-Induced Functional Renal Insufficiency in Patients with Bilateral Renal-Artery Stenoses or Renal-Artery Stenosis in a Solitary Kidney
660 Citations1983Donald E. Hricik, Philip J. Browning +4 more
A variety of mechanisms have been postulated to account for captopril-based renal failure and these include angiotensin-converting-enzyme inhibitor-like mechanisms, cell reprograming, and “spatially masked” mechanisms.
CirculationLeft ventricular volume from paired biplane two-dimensional echocardiography.
610 Citations1979N B Schiller, Harry Acquatella +10 more
The volumes determined from the minor-axis dimensions of M-mode echograms in 23 of the same patients correlated poorly with angiography, and the volumes determined with a modified Simpson's rule formula determined systolic and diastolic left ventricular volumes from the bi plane echogram and the biplane angiogram.
Urologic Clinics of North AmericaThe Natural History of Atherosclerotic and Fibrous Renal Artery Disease
525 Citations1984Martin J. Schreiber, Marc A. Pohl +1 more
Journal of the American Society of NephrologyRenal artery stenosis
461 Citations1992Michael B. Harding, Lloyd R. Smith +7 more
Data reveal the previously undetected high prevalence of renal artery disease in patients undergoing cardiac catheterization and provide clinical and angiographic features that assist in predicting its presence and develop a model that predicts the highest-risk subset of patients who have significant renal artery narrowing.
American Journal of Kidney DiseasesRenal Vascular Disease Causing End-Stage Renal Disease, Incidence, Clinical Correlates, and Outcomes: A 20-Year Clinical Experience
376 Citations1994Lionel U. Mailloux, Barbara Napolitano +4 more
It is felt that a significant number of elderly white hypertensive patients described in the 1992 US Renal Data Service report have renal vascular disease as a cause of end-stage renal disease, highlighting the need to establish correct renal diagnoses.
Journal of Vascular SurgeryNatural history of atherosclerotic renal artery stenosis: A prospective study with duplex ultrasonography
272 Citations1994R. Eugene Zierler, Robert O. Bergelin +2 more
Progression of renal artery stenosis, as defined in this study, occurs at a rate of approximately 20% per year and is associated with a marked decrease in kidney length.
The American Journal of MedicineRenal artery stenosis: A common and important problem in patients with peripheral vascular disease
231 Citations1994Constantinos G. Missouris, T.M. Buckenham +2 more
Renal artery stenosis is a common independent feature in patients with peripheral vascular disease, and its prevalence increases with the increasing severity of the peripheral vascular Disease.
RadiologyThree-dimensional gadolinium-enhanced MR angiography for aortoiliac inflow assessment plus renal artery screening in a single breath hold.
213 Citations1996John J. Snidow, Mark S. Johnson +6 more
This breath-hold protocol improves the accuracy of aortoiliac inflow assessment, but low resolution limits evaluation of small renal arteries.
BMJStenosis of Renal Artery: An Unselected Necropsy Study
159 Citations1964C. J. Schwartz, T. A. White
The prevalence and distribution of renal arterial stenosis is determined in both the extrarenal and intrarenal segments of the arterial tree and the relation of stenosis to various clinical and pathological parameters is discussed.
PubMedConsensus report on ACE inhibitor renography for detecting renovascular hypertension. Radionuclides in Nephrourology Group. Consensus Group on ACEI Renography.
139 Citations1996Andrew Taylor, Joseph V. Nally +14 more
A comparative assessment of deconvolution and diuresis rcnography in equivocal upper urinary tract obstruction and clinical applications of renal scintigraphy is presented.
QJMPresentation, clinical features and outcome in different patterns of atherosclerotic renovascular disease
98 Citations1994J.O. CONNOLLY, Robert Higgins +5 more
In non-diabetic subjects, PCTA resulted in stabilization of renal function for at least one year in nearly three-quarters of cases, which suggests a benefit from intervention in this disease whose natural history is otherwise of progression.
PubMedThe pathology of chronic renal ischemia.
93 Citations1996Shanley Pf
Mechanisms determining the varied and complex pathological findings that may be observed in individual cases are outlined.
Journal of Interventional CardiologyIncidence of Renal Artery Stenosis in Hypertensive Patients Undergoing Coronary Angiography
90 Citations1989George W. Vetrovec, Douglas M. Landwehr +1 more
Significant renal artery stenosis was identified in 23% of patients with hypertension and/or renal insufficiency suggesting that more vigorous consideration of renal arteries stenosis may be appropriate in hypertensive patients with coronary artery disease, and abdominal angiography in conjunction with coronary Angiography appears to be a useful screening test for renal artery surgery.
HypertensionRenal scintigraphic captopril test in the diagnosis of renovascular hypertension.
65 Citations1987Enza Fommei, S Ghione +7 more
Dynamic renal scintigraphy with 99mTc-DTPA before and 1 hour after administration of captopril was performed in a selected series of 39 hypertensive subjects with suspected renovascular hypertension, revealing renal artery stenosis in 12 and aortic coarctation in 2 subjects.
QJMRenovascular Disease and Renal Complications of Angiotensin-Converting Enzyme Inhibitor Therapy
62 Citations1990Philip A. Kalra, H. Mamtora +2 more
Renal complications of angiotensin-converting enzyme (ACE) inhibitor therapy are widely recognized, but few authors have documented the incidence or spectrum of these conditions.
American Journal of RoentgenologyDiagnosis of renovascular hypertension: feasibility of captopril-sensitized dynamic MR imaging and comparison with captopril scintigraphy.
58 Citations1996N. Grenier, Hervé Trillaud +6 more
Captopril-sensitized dynamic MR imaging of the kidney is feasible in patients with renovascular hypertension, however, captoprill-induced changes are not present in all patients proven to have the disease.
American Journal of HypertensionCaptopril Renography and the Effect of Percutaneous Transluminal Angioplasty on Blood Pressure in 94 Patients With Renal Artery Stenosis
47 Citations1991G. G. Geyskes, A. J. G. d. Bruyn
Captopril renography is a useful investigation in assessing the likelihood of blood pressure reduction after PTA of renal artery stenosis, and it would have been better not to have performed angiography and PTA at all.
Postgraduate Medical JournalPatients with atherosclerotic renovascular disease presenting to a renal unit: an audit of outcome
38 Citations1993J. E. Scoble, P. Sweny +2 more
Patients presenting with impaired renal function and atherosclerotic renovascular disease can have useful improvement in renal function with revascularization without any detriment to survival.
American Journal of NephrologyProspective Study on Captopril Renography in Hypertensive Patients
29 Citations1992Dario Roccatello, Giuseppe Picciotto +4 more
Six hundred and sixty-seven hypertensive patients were analyzed by captopril-enhanced scintigraphy and the renogram was defined highly suggestive of renovascular hypertension.
British Journal of RadiologyIntravascular contrast media
26 Citations1982Ronald G. Grainger
One of the great pleasures in attempting to research into and to review a major facet of medical hiustory is that it may bring the researcher into contact with some of theGreat personalities involved.
PubMedCaptopril renal scintigraphy in patients with hypertension and chronic renal failure.
23 Citations1994Ioannis Datseris, Jamshed Bomanji +5 more
In hypertensive patients with renal failure, captopril renal scintigraphy can be utilized to identify the presence of angiotensin II-dependent renal dysfunction and possibly help to predict the beneficial effect of ACE inhibitor therapy.
PubMedCellular and metabolic consequences of chronic ischemia on kidney function.
18 Citations1996P S Kellerman
This work has shown the primary dependence of the stenotic kidney on angiotensin II in maintenance of glomerular filtration rate is from studies of renovascular hypertension, although other vascular regulators, such as endothelium-derived nitric oxide and endothelin, may also play a role.
PubMedRenovascular hypertension: the small kidney updated.
8 Citations1988G. G. Geyskes, H. Y. Oel +4 more
