Clinical Pharmacology of Nicotine
Annual Review of MedicinePublished 1 February 1986
Neal L. Benowitz
Citations275
SJR quartileQ1
SJR score6.79
SNIP4.24
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TL;DR
This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
Abstract
Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
Keywords
PsychologyChemistryBiochemistry, Genetics and Molecular Biology
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Heart rate-systolic pressure product, cardiac output and maximal first derivative of left ventricular pressure (dP/dt) without significantly changing the coronary sinus concentrations of thromboxane B2 or 6-keto-prostaglandin F1 alpha (the stable metabolites of throttle A2 and prostacyclin, respectively).
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94 Citations1974Wilbert S. Aronow, John Cassidy +7 more
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53 Citations1980Åke Wennmalm
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The antidiuretic response to nicotine appears to be a useful means of assessing hypothalamic function in man and may be postulated to account for polyuria.
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