The Meso-Telencephalic Dopamine Neuron System: A Review of Its Anatomy

The unmyelinated and sparsely myelinated fibre systems probably comprise the vast majority of connections in the central nervous system and their anatomy was virtually unknown until the staining methods for degenerating fibres were introduced.

Abstract

The unmyelinated and sparsely myelinated fibre systems probably comprise the vast majority of connections in the central nervous system. Until the staining methods for degenerating fibres were introduced, their anatomy was, however, virtually unknown. The subsequent development of a new arsenal of histochemical and autoradio-graphic tracing techniques has meant a mere revolution in our understanding of the organization of many functional systems in the brain, not least the limbic system.