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Executive dysfunction predicts nonresponse to fluoxetine in major depression

Journal of Affective DisordersPublished 1 October 2000
Jennifer J. Dunkin, Andrew F. Leuchter, Ian A. Cook, Julia Kasl‐Godley, Michelle Abrams, Susan Rosenberg-Thompson
Citations220
SJR quartileQ1
SJR score2.12
SNIP1.65

TL;DR

The findings suggest that subtle prefrontal dysfunction in subjects with major depression may be predictive of poor response with particular medications.

Abstract

The findings suggest that subtle prefrontal dysfunction in subjects with major depression may be predictive of poor response with particular medications. Assessment of the executive functions may play a particular role in pretreatment identification of subjects likely to respond to specific medications.

Keywords

PsychologyMedicineNeuroscience