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Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions

Biological PsychiatryPublished 24 February 2004
Mila Roceri, Francesca Cirulli, Cassandra Pessina, Paolo Peretto, Giorgio Racagni, Marco Andrea Riva
Citations311
SJR quartileQ1
SJR score4.68
SNIP2.24

TL;DR

The data suggest that postnatal repeated maternal deprivation produces a significant reduction of BDNF expression within prefrontal cortex and striatum, which may render these structures less plastic and more vulnerable under challenging conditions.

Abstract

Our data suggest that MD produces a significant reduction of BDNF expression within prefrontal cortex and striatum, which may render these structures less plastic and more vulnerable under challenging conditions.

Keywords

PsychologyMedicineNeuroscience